CAS 13100-69-1

5,6-Epoxy-5,6-dihydroretinoic acid

Description:

5,6-Epoxy-5,6-dihydroretinoic acid, with the CAS number 13100-69-1, is a derivative of retinoic acid, which is a metabolite of vitamin A. This compound features an epoxy group, indicating the presence of an epoxide functional group, which contributes to its reactivity and biological activity. It is characterized by its role in various biochemical processes, particularly in the regulation of gene expression and cellular differentiation. The compound is known to interact with nuclear receptors, influencing developmental pathways and potentially exhibiting effects on cell growth and apoptosis. Its structural features include a polyene chain, which is typical of retinoids, and it may exhibit isomerism due to the presence of multiple double bonds. The compound is of interest in pharmacological research, particularly in the context of skin health and cancer treatment, due to its potential therapeutic properties. However, its stability and solubility in biological systems can vary, affecting its bioavailability and efficacy.

Formula: C₂₀H₂₈O₃

InChI: InChI=1/C20H28O3/c1-15(8-6-9-16(2)14-17(21)22)10-13-20-18(3,4)11-7-12-19(20,5)23-20/h6,8-10,13-14H,7,11-12H2,1-5H3,(H,21,22)/b9-6+,13-10+,15-8+,16-14+

InChI key: InChIKey=KEEHJLBAOLGBJZ-WEDZBJJJNA-N

SMILES: C(=C/C(=C/C=C/C(=C/C(O)=O)/C)/C)\C12C(C)(O1)CCCC2(C)C

Synonyms:

• 5,6-Dihydro-5,6-Epoxyretinoic Acid
• 5,6-Epoxy-5,6-dihydroretinoic acid
• 5,6-Epoxy-atRA
• 5,6-Epoxyretinoic Acid
• Retinoic acid, 5,6-epoxy-5,6-dihydro-
• all-trans-5,6-Epoxyretinoic acid

Tretinoin EP Impurity G

CAS: 13100-69-1

Formula: C₂₀H₂₈O₃

Molecular weight: 316.44

Ref: ST-EA-CP-T101023

5,6-Epoxyretinoic acid

CAS: 13100-69-1

5,6-Epoxyretinoic acid

Purity: 98%

Molecular weight: 316.43g/mol

Ref: 54-OR1075443

5,6-Epoxy-all-trans-Retinoic Acid

CAS: 13100-69-1

Formula: C₂₀H₂₈O₃

Color and Shape: Yellow Solid

Molecular weight: 316.44

Ref: 4Z-T-114013

all-trans-5,6-epoxy Retinoic Acid

CAS: 13100-69-1

all-trans-5,6-epoxy Retinoic Acid can be used in related research in the field of life sciences. Its product number is T36382 and CAS number is 13100-69-1.

Formula: C₂₀H₂₈O₃

Color and Shape: Solid

Molecular weight: 316.43

Ref: TM-T36382

all-trans 5,6-Epoxy Retinoic Acid

Controlled Product

CAS: 13100-69-1

Stability Light Sensitive, Temperature Sensitive
Applications A metabolite of all-trans Retinoic acid (R250200).
References Idres, N., et al.: Cancer Res., 61, 700 (2001), Taimi, M., et al.: J. Biol. Chem., 279, 77 (2004), Vermot, J., et al.: Science, 308, 563 (2005),

Formula: C₂₀H₂₈O₃

Color and Shape: Light Yellow

Molecular weight: 316.43

Ref: TR-E589800

all-trans 5,6-Epoxy retinoic acid

CAS: 13100-69-1

5,6-Epoxy retinoic acid is a synthetic retinoid that has been shown to have biological properties in tissue culture and rat liver microsomes. It is an agonist of the retinoic acid receptor (RAR) and binds to DNA at the same site as all-trans retinoic acid. 5,6-Epoxyretinoic acid also has effects on gene expression in human serum and inhibits the proliferation of cancer cells by inducing apoptosis. The synthetic retinoid can be used as a novel chemotherapeutic agent for breast cancer or leukemia.

Formula: C₂₀H₂₈O₃

Purity: Min. 95 Area-%

Color and Shape: Yellow Powder

Molecular weight: 316.43 g/mol

Ref: 3D-FE17290

5,6-Epoxy-All-Trans-Retinoic Acid

CAS: 13100-69-1

Formula: C₂₀H₂₈O₃

Molecular weight: 316.44

Ref: ST-EA-CP-I25012