CAS 1310676-34-6

TRANS-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE, HYDROCHLORIDE

Description:

TRANS-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE, HYDROCHLORIDE, identified by its CAS number 1310676-34-6, is a chemical compound characterized by its complex structure, which includes a naphthalene core and a dichlorophenyl substituent. This compound typically appears as a white to off-white crystalline solid and is soluble in water and various organic solvents, which is indicative of its polar functional groups. The presence of the hydrochloride salt form enhances its solubility and stability, making it suitable for pharmaceutical applications. Its molecular structure suggests potential biological activity, particularly in the context of medicinal chemistry, where it may exhibit properties relevant to neuropharmacology or other therapeutic areas. Safety and handling precautions are essential, as with many organic compounds, due to potential toxicity or environmental impact. As with any chemical, thorough understanding of its properties, reactivity, and safety data is crucial for effective utilization in research or industrial applications.

Formula: C₁₆H₁₆Cl₃N

Synonyms:

• rac-trans-N-Desmethyl Sertraline Hydrochloride
• TRANS-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE, HYDROCHLORIDE

(±)-trans-N-Desmethylsertralin1,2,2-d3 HCl

CAS: 1310676-34-6

Purity: 98 atom % D

Molecular weight: 331.69

Ref: 3U-D7740

rac-trans-N-Desmethyl sertraline hydrochloride

CAS: 1310676-34-6

Racemic trans-N-desmethyl sertraline hydrochloride, also known as desmethylsertraline or N-desmethylsertraline, is a member of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants. It has been found to have nootropic effects in animal studies and to attenuate some of the behavioural effects of amphetamine in rats. Racemic trans-N-desmethyl sertraline hydrochloride is a chiral compound with two enantiomers, ("R")-(+)-trans-N-desmethyl sertraline and ("S")-(−)-trans-N-desmethyl sertraline, which are mirror images of each other. The drug is marketed as a racemate; however, only the "R" enantiomer is active. Racemic trans-N-desmethyl sertraline hydrochloride has not been shown to produce any clinically significant drug interactions.

Formula: C₁₆H₁₆Cl₃N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.66 g/mol

Ref: 3D-FR27665

rac-trans-N-Desmethyl Sertraline-d3 Hydrochloride

Controlled Product

CAS: 1310676-34-6

Applications rac-trans-N-Desmethyl Sertraline-d3 Hydrochloride is deuterium labelled rac-trans-N-Desmethyl Sertraline Hydrochloride (D292117), which is a metabolite of Sertraline. rac-trans-N-Desmethyl Sertraline-d3 Hydrochloride can be used for treating CNS disorders.
References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)

Formula: C₁₆H₁₂D₃Cl₂N•HCl

Color and Shape: Neat

Molecular weight: 331.68

Ref: TR-D292117