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CAS 131123-76-7

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5,7-dichlorokynurenic acid sodium

Description:
5,7-Dichlorokynurenic acid sodium is a chemical compound that serves as a potent antagonist of the NMDA (N-methyl-D-aspartate) receptor, which is involved in synaptic plasticity and memory function. This compound is a derivative of kynurenic acid, characterized by the presence of two chlorine atoms at the 5 and 7 positions of the aromatic ring. As a sodium salt, it is typically more soluble in aqueous solutions, which enhances its bioavailability for research and potential therapeutic applications. The compound is of interest in neuropharmacology due to its potential effects on neurodegenerative diseases and psychiatric disorders. Its mechanism of action involves modulation of glutamate signaling, which is crucial for neuronal communication. Additionally, 5,7-dichlorokynurenic acid sodium may exhibit antioxidant properties, contributing to its neuroprotective effects. Safety and handling precautions should be observed, as with any chemical substance, to mitigate risks associated with exposure.
Formula:C10H4Cl2NNaO3
InChI:InChI=1/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16)
InChI key:InChIKey=BGKFPRIGXAVYNX-UHFFFAOYSA-N
SMILES:OC=1C2=C(N=C(C(O)=O)C1)C=C(Cl)C=C2Cl
Synonyms:
  • 2-Quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-
  • 5,7-Dcka
  • 5,7-Dichloro-4-Oxo-1,4-Dihydroquinoline-2-Carboxylic Acid
  • 5,7-Dichloro-4-hydroxy-2-quinolinecarboxylic acid
  • 5,7-Dichlorokynurenic acid
  • 5,7-Dichloroquinurenic acid
  • 5,7-Dichorokynurenic acid
  • Kynurenic acid, 5,7-dichloro-
  • 5,7-Dichloro-4-hydroxyquinoline-2-carboxylicacidsodiumsalt
  • 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID
  • See more synonyms
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