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CAS 131176-01-7

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cyclo(phenylalanyl-4-fluoro-prolyl)

Description:
Cyclo(phenylalanyl-4-fluoro-prolyl), with the CAS number 131176-01-7, is a cyclic dipeptide that features a unique combination of amino acids, specifically phenylalanine and proline, with a fluorine substitution on the proline residue. This compound exhibits characteristics typical of cyclic peptides, such as increased stability compared to linear peptides due to its closed structure, which can enhance its resistance to enzymatic degradation. The presence of the fluorine atom can influence the compound's biological activity, potentially affecting its interaction with biological targets and altering its pharmacokinetic properties. Cyclo(phenylalanyl-4-fluoro-prolyl) may exhibit specific conformational preferences that can be crucial for its function in biological systems. Additionally, the aromatic nature of phenylalanine contributes to hydrophobic interactions, while proline's unique cyclic structure can introduce rigidity into the peptide chain. Such features make this compound of interest in medicinal chemistry and drug design, particularly in the development of peptide-based therapeutics.
Formula:C14H15FN2O2
InChI:InChI=1/C14H15FN2O2/c15-10-7-12-13(18)16-11(14(19)17(12)8-10)6-9-4-2-1-3-5-9/h1-5,10-12H,6-8H2,(H,16,18)/t10-,11+,12+/m0/s1
Synonyms:
  • Cylco(phe-4-F-pro)
  • c(Phe-fpro)
  • (3R,7S,8aR)-3-benzyl-7-fluorohexahydropyrrolo[1,2-a]pyrazine-1,4-dione
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