CAS 1312547-19-5

Samatasvir

Description:

Samatasvir is an antiviral compound primarily investigated for its potential use in the treatment of hepatitis C virus (HCV) infections. It belongs to a class of drugs known as NS5A inhibitors, which target the NS5A protein crucial for viral replication and assembly. The chemical structure of Samatasvir includes specific functional groups that contribute to its activity and solubility. It exhibits a favorable pharmacokinetic profile, allowing for effective absorption and distribution in the body. The compound has shown promise in clinical trials, often in combination with other antiviral agents to enhance therapeutic efficacy and reduce the likelihood of resistance. Safety and tolerability profiles are also important characteristics, as they determine the suitability of the drug for patient populations. Overall, Samatasvir represents a significant advancement in the ongoing efforts to develop effective treatments for HCV, contributing to the broader landscape of antiviral drug development.

Formula: C₄₇H₄₈N₈O₆S₂

InChI: InChI=1S/C47H48N8O6S2/c1-26(2)38(52-46(58)60-3)44(56)55-21-9-13-37(55)43-49-33-19-18-30(22-34(33)50-43)32-25-63-40-31(24-62-41(32)40)27-14-16-28(17-15-27)35-23-48-42(51-35)36-12-8-20-54(36)45(57)39(53-47(59)61-4)29-10-6-5-7-11-29/h5-7,10-11,14-19,22-26,36-39H,8-9,12-13,20-21H2,1-4H3,(H,48,51)(H,49,50)(H,52,58)(H,53,59)/t36-,37-,38-,39+/m0/s1

InChI key: InChIKey=ATOLIHZIXHZSBA-BTSKBWHGSA-N

SMILES: C([C@@H](NC(OC)=O)[C@H](C)C)(=O)N1[C@H](C=2NC3=CC(C=4C5=C(C(=CS5)C6=CC=C(C=C6)C=7NC(=NC7)[C@H]8N(C([C@H](NC(OC)=O)C9=CC=CC=C9)=O)CCC8)SC4)=CC=C3N2)CCC1

Synonyms:

• Carbamic acid, N-[(1R)-2-[(2S)-2-[5-[4-[6-[2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1H-benzimidazol-6-yl]thieno[3,2-b]thien-3-yl]phenyl]-1H-imidazol-2-yl]-1-pyrrolidinyl]-2-oxo-1-phenylethyl]-, methyl ester
• IDX 719
• IDX 18719
• Samatasvir

Samatasvir

CAS: 1312547-19-5

Samatasvir

Purity: ≥98%

Molecular weight: 885.06g/mol

Ref: 54-BUP03417

Samatasvir

CAS: 1312547-19-5

Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.

Formula: C₄₇H₄₈N₈O₆S₂

Purity: 98.03%

Color and Shape: Solid

Molecular weight: 885.06

Ref: TM-T9567