CAS 131334-43-5

H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH

Description:

The chemical substance with the name "H-HIS-CYS-LEU-GLY-LYS-TRP-LEU-GLY-HIS-PRO-ASP-LYS-PHE-OH" and CAS number "131334-43-5" is a peptide composed of a sequence of amino acids. This peptide features a variety of functional groups characteristic of amino acids, including amine, carboxylic acid, and hydroxyl groups, which contribute to its solubility and reactivity. The presence of histidine, cysteine, and tryptophan suggests potential for metal ion coordination and antioxidant properties, while the lysine and aspartic acid residues may influence its charge and interaction with biological systems. The peptide's structure allows for various conformations, which can affect its biological activity, stability, and interactions with other molecules. Peptides like this one are often studied for their roles in biological processes, potential therapeutic applications, and as models for understanding protein folding and function. Overall, this substance exemplifies the complexity and diversity of peptide chemistry in biological systems.

Formula: C₇₂H₁₀₄N₂₀O₁₆S

Synonyms:

• Lipophilin (139-151) (Depalmitoylated) (Human, Bovine, Dog, Mouse, Rat)
• His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe
• H-His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-Oh (Human, Bovine, Dog, Mouse, Rat)
• Plp (139-151) (Depalmitoylated) (Human, Bovine, Dog, Mouse, Rat)
• Myelin Proteolipid Protein (139-151) (Depalmitoylated) (Human, Bovine, Dog, Mouse, Rat)

PLP (139-151)

CAS: 131334-43-5

PLP (139-151) is amino acid residue residue 139 to 151 of myelin proteolipid protein (PLP). This peptide is used to induce relapsing-remitting (RR)-EAE model.

Formula: C₇₂H₁₀₄N₂₀O₁₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1537.79

Ref: TM-TP1282

Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) trifluoroacetate salt

CAS: 131334-43-5

MPLP(139-151) is a peptide that is derived from the myelin proteolipid protein (PLP). MPLP(139-151) has been shown to inhibit macrophage inflammatory in vitro and brain inflammation in vivo. The inhibition of macrophages was mediated by the induction of apoptosis and inhibition of NF-κB. MPLP(139-151) also induced regression of experimental autoimmune encephalomyelitis in mice, which suggests that it might be useful as a therapeutic agent for multiple sclerosis or other inflammatory diseases.

Formula: C₇₂H₁₀₄N₂₀O₁₆S

Purity: Min. 95%

Molecular weight: 1,537.79 g/mol

Ref: 3D-FM109654