ICMT-IN-55, with the CAS number 1313602-77-5, is a chemical compound that has been studied primarily for its potential role as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT). This enzyme is involved in the post-translational modification of proteins, particularly those that are prenylated, which is crucial for their proper localization and function within cells. The compound is characterized by its specific molecular structure, which allows it to interact with the active site of ICMT, thereby inhibiting its activity. This inhibition can have significant implications in various biological processes, including cell signaling and proliferation. ICMT-IN-55 is typically evaluated in the context of cancer research, as targeting ICMT may provide therapeutic avenues for certain malignancies. As with many chemical substances, its solubility, stability, and bioavailability are important factors that influence its efficacy and potential applications in medicinal chemistry. Further studies are often required to fully understand its pharmacokinetics and pharmacodynamics.

ICMT-IN-55

1313602-77-5: ICMT-IN-55, with the CAS number 1313602-77-5, is a chemical compound that has been studied primarily for its potential role as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT). This enzyme is involved in the post-translational modification of proteins, particularly those that are prenylated, which is crucial for their proper localization and function within cells. The compound is characterized by its specific molecular structure, which allows it to interact with the active site of ICMT, thereby inhibiting its activity. This inhibition can have significant implications in various biological processes, including cell signaling and proliferation. ICMT-IN-55 is typically evaluated in the context of cancer research, as targeting ICMT may provide therapeutic avenues for certain malignancies. As with many chemical substances, its solubility, stability, and bioavailability are important factors that influence its efficacy and potential applications in medicinal chemistry. Further studies are often required to fully understand its pharmacokinetics and pharmacodynamics.

ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].

CAS 1313602-77-5

ICMT-IN-55

ICMT-IN-55

Ref: TM-T86702