CAS 1313883-00-9

ARQ 092

Description:

ARQ 092, also known by its chemical name, is a small molecule inhibitor primarily targeting the AKT signaling pathway, which plays a crucial role in cell growth, proliferation, and survival. It is classified as a selective inhibitor of the AKT family of serine/threonine kinases, particularly AKT1, AKT2, and AKT3. This compound has been investigated for its potential therapeutic applications in various cancers, especially those characterized by aberrant AKT signaling. ARQ 092 exhibits properties that allow it to interfere with the phosphorylation of downstream targets of AKT, thereby inhibiting tumor growth and promoting apoptosis in cancer cells. Its pharmacological profile includes oral bioavailability and a favorable safety profile in preclinical studies. As a research compound, ARQ 092 has been evaluated in clinical trials, focusing on its efficacy and safety in patients with specific malignancies. However, as with any investigational drug, ongoing studies are essential to fully understand its therapeutic potential and any associated risks.

Formula: C₂₇H₂₅ClN₆

Synonyms:

• Miransertib (ARQ 092) HCl
• ARQ092 Hydrochloride
• Miransertib HCl
• ARQ092 HCl

Miransertib (ARQ 092) HCl

CAS: 1313883-00-9

Formula: C₂₇H₂₅ClN₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 468.9806

Ref: IN-DA01EB1I

3-(3-(4-(1-Aminocyclobutyl)Phenyl)-5-Phenyl-3H-Imidazo[4,5-B]Pyridin-2-Yl)Pyridin-2-Amine Hydrochloride

CAS: 1313883-00-9

3-(3-(4-(1-Aminocyclobutyl)Phenyl)-5-Phenyl-3H-Imidazo[4,5-B]Pyridin-2-Yl)Pyridin-2-Amine Hydrochloride

Purity: 98%

Molecular weight: 468.98g/mol

Ref: 54-OR1030909

Miransertib hydrochloride

CAS: 1313883-00-9

Miransertib hydrochloride is an orally active, selective, allosteric pan-Akt inhibitor that also demonstrates potent activity against Leishmania parasites.

Formula: C₂₇H₂₅ClN₆

Purity: 99.81%

Color and Shape: Solid

Molecular weight: 468.98

Ref: TM-T22247

Miransertib (ARQ 092) HCl

CAS: 1313883-00-9

Miransertib (ARQ 092) HCl is a selective inhibitor, which is a synthetic small molecule specifically targeting the AKT pathway. It is sourced through specialized chemical synthesis designed to interfere with key signaling pathways implicated in the proliferation and survival of cancer cells. The mode of action involves the inhibition of the serine/threonine kinase AKT, an integral part of the PI3K/AKT/mTOR signaling pathway that is frequently dysregulated in various cancers.

Formula: C₂₇H₂₅ClN₆

Purity: Min. 95%

Molecular weight: 468.98 g/mol

Ref: 3D-NCC88300