CAS 13139-15-6

BOC-L-leucine

Description:

BOC-L-leucine, with the CAS number 13139-15-6, is a derivative of the amino acid leucine, which is essential for protein synthesis and various metabolic processes. This compound features a tert-butyloxycarbonyl (BOC) protecting group attached to the amino group of L-leucine, making it useful in peptide synthesis and organic chemistry. BOC-L-leucine is typically a white to off-white crystalline solid, and it is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. The BOC group serves to protect the amino functionality during chemical reactions, allowing for selective modifications of other functional groups. Upon deprotection, BOC-L-leucine can participate in further reactions to form peptides or other derivatives. Its stability and reactivity make it a valuable intermediate in the synthesis of pharmaceuticals and biochemicals. As with many chemical substances, proper handling and storage are essential to maintain its integrity and ensure safety in laboratory settings.

Formula: C₁₁H₂₁NO₄

InChI: InChI=1S/C11H21NO4/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14)/t8-/m0/s1

InChI key: InChIKey=MDXGYYOJGPFFJL-QMMMGPOBSA-N

SMILES: [C@H](NC(OC(C)(C)C)=O)(CC(C)C)C(O)=O

Synonyms:

• (2R)-2-[(tert-butoxycarbonyl)amino]-4-methylpentanoate
• (2S)-2-[(tert-Butoxycarbonyl)amino]-4-methylpentanoic acid
• (2S)-2-[(tert-butoxycarbonyl)amino]-4-methylpentanoate
• (2S)-2-[[(tert-Butoxy)carbonyl]amino]-4-methylpentanoic acid
• (2S)-4-Methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
• (S)-2-[(tert-Butoxycarbonyl)amino]-4-methylpentanoic acid
• (S)-N-(t-Butoxycarbonyl)leucine
• <span class="text-smallcaps">L</span>-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
• BOC-<span class="text-smallcaps">L</span>-Leu-OH
• BOC-<span class="text-smallcaps">L</span>-leucine
• BOC-L-Leu-OH
• Boc-L-leucine
• Boc-Leu-OH.H2O
• Boc-Leu-OH・H2O
• L-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-
• Leucine, N-carboxy-, N-tert-butyl ester
• Leucine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-
• Leucine, N-carboxy-, N-tert-butyl ester, L-
• N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-leucine
• N-(tert-Butoxycarbonyl)-L-leucine
• N-(tert-butoxycarbonyl)-L-leucine monohydrate
• N-(tert-butoxycarbonyl)leucine
• N-(α-tert-Butoxycarbonyl)leucine
• N-Boc-<span class="text-smallcaps">L</span>-leucine
• N-Boc-L-leucine hydrate
• N-Carboxy-<span class="text-smallcaps">L</span>-leucine N-tert-butyl ester
• N-Carboxy-L-leucine N-tert-butyl ester
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-leucine
• N-[(1,1-Dimethylethoxy)carbonyl]-L-leucin
• N-[(1,1-Dimethylethoxy)carbonyl]leucine
• N-[(1,1-dimetiletoxi)carbonil]-L-leucina
• N-tert-Butoxycarbonylleucine
• Nsc 108690
• tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-leucine
• tert-Butoxycarbonyl-L-leucine

Boc-Leu-OH · H₂O

CAS: 13139-15-6

Bachem ID: 4001021.

Formula: C₁₁H₂₁NO₄·H₂O

Purity: > 99%

Color and Shape: White

Molecular weight: 249.31

Ref: 01-4001021

Boc-Leu-OH hydrate

CAS: 13139-15-6

Formula: C₁₁H₂₁NO₄·xH₂O

Purity: (Titration) ≥ 98.0%

Color and Shape: White to almost white powder

Molecular weight: 231.29 (anhydrous)

Ref: 7W-GM1662

L-Leucine, N-BOC protected

CAS: 13139-15-6

L-Leucine, N-BOC protected

Formula: C₁₁H₂₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.28873

Ref: 54-OR8774

Boc-L-Leu-OH

CAS: 13139-15-6

Formula: C₁₁H₂₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 231.2887

Ref: IN-DA00HSGE

tert-Butoxycarbonyl-L-leucine

Controlled Product

CAS: 13139-15-6

Applications Protected amino acid with antimicrobial activity.
References Oancea, S. et al.: J. Med. Biochem. 3, 239 (1999)

Formula: C₁₁H₂₁NO₄

Color and Shape: Neat

Molecular weight: 231.29

Ref: TR-B690575

BOC-Leu-OH monohydrate

CAS: 13139-15-6

Formula: C₁₁H₂₁NO₄·H₂O

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 249.31

Ref: 7W-GK2576

Boc-Leu-OH

CAS: 13139-15-6

Boc-L-Leucine

Formula: C₁₁H₂₁NO₄

Purity: 97% (contains <10%H2O)

Molecular weight: 231.29

Ref: IN-DG01260272

Boc-Leu-OH • 2O

CAS: 13139-15-6

Boc-Leu-OH • 2O is a monomer for the synthesis of peptides. It is hydrophobic and can be used as a polymer matrix for the synthesis of polypeptides. Boc-Leu-OH • 2O is obtained from nature and can be prepared by hydrolysis of chloroformate ester or hydrogen chloride in dioxane.
Boc-Leu-OH • 2O has been shown to have chiral properties and can be detected using microscopy, dichroism, or amino acid analysis.

Formula: C₁₁H₂₁NO₄•H₂O

Purity: Min. 95%

Molecular weight: 249.31 g/mol

Ref: 3D-BLL-2055

tert-Butoxycarbonyl-L-leucine

CAS: 13139-15-6

Tert-Butoxycarbonyl-L-leucine (tBOC-LL) is a tetrapeptide that is used as a drug substance in the synthesis of buserelin, a synthetic peptide hormone. It has been shown to have high reactivity in organic solvents and can be used in cationic polymerization reactions. tBOC-LL has been used to synthesize helical structures with high purity and yield. As it is not an amino acid, tBOC-LL does not occur naturally and must be synthesized.
Tert-Butoxycarbonyl-L-leucine (tBOC-LL) is available from Sigma Aldrich Chemie GmbH & Co KG as:

Formula: C₁₁H₂₁NO₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 231.29 g/mol

Ref: 3D-FB19425

Boc-Leu-OH

CAS: 13139-15-6

M03295 - Boc-Leu-OH

Formula: C₁₁H₂₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 231.292

Ref: 10-M03295

BOC-L-Leucine Monohydrate extrapure, 99%

CAS: 13139-15-6

Formula: C₁₁H₂₁NO₄·H₂O

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 249.31

Ref: SR-25833