CAS 13139-86-1

(4-Methoxyphenyl)magnesium bromide

Description:

(4-Methoxyphenyl)magnesium bromide is an organomagnesium compound, specifically a Grignard reagent, characterized by the presence of a methoxy group attached to a phenyl ring. This compound typically appears as a white to light yellow solid and is highly reactive, particularly with moisture and air, necessitating handling under an inert atmosphere, such as nitrogen or argon. It is soluble in non-polar solvents like diethyl ether or tetrahydrofuran, which are commonly used in reactions involving Grignard reagents. The presence of the methoxy group enhances the nucleophilicity of the phenyl ring, making it a valuable reagent in organic synthesis for forming carbon-carbon bonds. It can participate in various reactions, including nucleophilic additions to carbonyl compounds, leading to the formation of alcohols. However, due to its reactivity, it must be used with caution, as it can react violently with water and other protic solvents, releasing flammable hydrocarbons. Proper storage and handling protocols are essential to ensure safety and stability.

Formula: C₇H₇BrMgO

InChI: InChI=1S/C7H7O.BrH.Mg/c1-8-7-5-3-2-4-6-7;;/h3-6H,1H3;1H;/q;;+1/p-1

InChI key: InChIKey=JKXAZEXIOPFJSC-UHFFFAOYSA-M

SMILES: [Mg](Br)C1=CC=C(OC)C=C1

Synonyms:

• (4-Methoxyphenyl)Magnesium(1+) Bromide
• (4-Methoxyphenyl)magnesium bromide
• (p-Anisyl)bromomagnesium
• 4-Anisylmagnesium bromide
• 4-Methoxyphenylmagnesium bromide solution
• Bromo(4-Methoxyphenyl)Magnesium
• Bromo(p-methoxyphenyl)magnesium
• Magnesium Bromide Methoxybenzenide
• Magnesium, bromo(4-methoxyphenyl)-
• Magnesium, bromo(p-methoxyphenyl)-
• p-Anisol magnesium bromide
• p-Anisylmagnesium bromide

4-Methoxyphenylmagnesium bromide, 0.5M in THF

CAS: 13139-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₇BrMgO

Color and Shape: Pale brown to dark brown, Slightly hazy liquid

Molecular weight: 211.34

Ref: 02-089435

4-Methoxyphenylmagnesium bromide 1M solution in THF

CAS: 13139-86-1

4-Methoxyphenylmagnesium bromide 1M solution in THF

Purity: ≥95%

Color and Shape: Yellow-Brown Liquid

Molecular weight: 211.34g/mol

Ref: 54-OR320046

4-Methoxyphenylmagnesium bromide - 0.5M solution in THF

CAS: 13139-86-1

4-Methoxyphenylmagnesium bromide - 0.5M solution in THF is a cytotoxic agent that binds to the estrogen receptor, which is involved in breast cancer cell proliferation and differentiation. It is an azide that has been shown to react with hydrochloric acid to form an amide. This reaction may be stereoselective and involve dehydration of the amine group. The mechanism of this reaction involves the formation of a trifluoroacetic acid derivative, which undergoes unsaturated alkyl halogenation followed by chloride ion attack on the double bond. 4-Methoxyphenylmagnesium bromide - 0.5M solution in THF has been shown to inhibit the proliferation of human MCF-7 breast cancer cells, as well as other estrogen receptor modulators such as amines and trifluoroacetic acid.

Formula: C₇H₇BrMgO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 211.34 g/mol

Ref: 3D-FM146296

Magnesium, bromo(4-methoxyphenyl)-

CAS: 13139-86-1

Formula: C₇H₇BrMgO

Color and Shape: Liquid

Molecular weight: 211.3389

Ref: IN-DA000W3A