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CAS 131418-65-0

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sporeamicin A

Description:
Sporeamicin A is a naturally occurring antibiotic compound that belongs to the class of aminoglycosides. It is produced by certain strains of the bacterium Micromonospora, which is known for its ability to synthesize various bioactive metabolites. Sporeamicin A exhibits a unique structure characterized by a complex glycosidic framework, which contributes to its biological activity. This compound is primarily recognized for its antimicrobial properties, particularly against a range of Gram-positive bacteria. Its mechanism of action involves binding to the bacterial ribosome, thereby inhibiting protein synthesis, which ultimately leads to bacterial cell death. Additionally, sporeamicin A has shown potential in the treatment of certain infections, although its clinical use may be limited due to toxicity and resistance issues associated with aminoglycosides. Research continues to explore its pharmacological potential and the possibility of modifying its structure to enhance efficacy and reduce side effects. Overall, sporeamicin A represents an important compound in the field of antibiotic research and development.
Formula:C37H63NO12
InChI:InChI=1/C37H63NO12/c1-14-25-37(10)30(40)20(4)28(50-37)18(2)16-35(8,43)32(49-34-27(39)24(38(11)12)15-19(3)45-34)21(5)29(22(6)33(42)47-25)48-26-17-36(9,44-13)31(41)23(7)46-26/h18-19,21-27,29,31-32,34,39,41,43H,14-17H2,1-13H3/t18-,19?,21-,22+,23-,24-,25-,26-,27+,29-,31-,32?,34-,35?,36+,37+/m0/s1
Synonyms:
  • SRM-A
  • 9,10-Didehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxoerythromycin
  • (1R,2S,5R,6S,7S,11S)-8-{[(2S,3R,4S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-2-ethyl-9-hydroxy-6-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-1,5,7,9,11,13-hexamethyl-3,15-dioxabicyclo[10.2.1]pentadec-12-ene-4,14-dione (non-preferred name)
  • L53-18 A
  • Erythromycin, 9,10-didehydro-9-deoxo-11,12-dideoxy-9,12-epoxy-11-oxo-
  • Sporeamicin A
  • (2R,6S,7S,8R,11R,12R)-5-[(2S,3R,4S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-11-ethyl-4-hydroxy-7-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-2,4,6,8,12,14-hexamethyl-10,15-dioxabicyclo[10.2.1]pentadec-1(14)-ene-9,13-dione
  • 9,12-Epoxy-11-oxo-11,12-dideoxy-9,10-didehydro(9-deoxoerythromycin)
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