CAS 131438-74-9

amyloid B-protein fragment 1-38

Description:

Amyloid beta-protein fragment 1-38, often referred to as Aβ1-38, is a peptide associated with Alzheimer's disease and is a component of amyloid plaques found in the brains of affected individuals. This fragment is derived from the larger amyloid precursor protein (APP) and consists of 38 amino acids. Aβ1-38 is known for its ability to aggregate, forming oligomers and fibrils, which are implicated in neurotoxicity and the progression of Alzheimer's pathology. The peptide exhibits hydrophobic characteristics, contributing to its propensity to aggregate in aqueous environments. Additionally, it can interact with various cellular receptors and proteins, influencing neuronal signaling and health. The CAS number 131438-74-9 uniquely identifies this specific peptide in chemical databases, facilitating research and study. Understanding the properties and behavior of Aβ1-38 is crucial for developing therapeutic strategies aimed at mitigating its harmful effects in neurodegenerative diseases.

Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Synonyms:

• Amyloid .beta.-Protein (1-38)
• H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-OH

Amyloid β-Protein (1-38)

CAS: 131438-74-9

Like Aβ (25-35), the Aβ fragment (1-38) destabilizes calcium homeostasis and renders human cortical neurones vulnerable to environmental insults.

Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Purity: >95%

Color and Shape: White

Molecular weight: 4131.6

Ref: 01-4030204

Glycine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycyl-

CAS: 131438-74-9

Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Color and Shape: Solid

Molecular weight: 4131.5413

Ref: IN-DA000W6M

β-Amyloid (1-38)

CAS: 131438-74-9

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Molecular weight: 4,131.6 g/mol

Ref: 3D-PP50622

Amyloid β-Protein (Human, 1-38)

CAS: 131438-74-9

Amyloid β-Protein (Human, 1-38) is a peptide that is a major constituent of the amyloid plaques found in the brains of people with Alzheimer's disease. It has been shown to inhibit ion channels and ligand-activated ion channels. The receptor for this protein is unknown, but it may be involved in cell signaling or neurotransmitter release. Amyloid β-Protein (Human, 1-38) can be used as a research tool to study proteins and their interactions with other proteins, as well as to study how these interactions affect the function of cells. It can also be used to study how antibody molecules bind to specific proteins and how these antibodies interact with other molecules.

Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Purity: Min. 95%

Molecular weight: 4,131.5 g/mol

Ref: 3D-PAB-4484-V

Amyloid β-Protein (1-38) trifluoroacetate salt

CAS: 131438-74-9

Please enquire for more information about Amyloid beta-Protein (1-38) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₈₄H₂₇₇N₅₁O₅₆S

Purity: Min. 95%

Molecular weight: 4,131.54 g/mol

Ref: 3D-FA108828