CAS 1314795-11-3

Radalbuvir

Description:

Radalbuvir, identified by its CAS number 1314795-11-3, is an antiviral compound primarily investigated for its potential in treating hepatitis C virus (HCV) infections. It belongs to the class of non-nucleoside polymerase inhibitors, which function by interfering with the viral RNA polymerase, thereby inhibiting viral replication. Radalbuvir exhibits a unique mechanism of action that distinguishes it from traditional nucleoside analogs. The compound has shown promising results in preclinical and clinical studies, demonstrating efficacy against various HCV genotypes. Its pharmacokinetic profile suggests favorable absorption and distribution characteristics, although specific details regarding its metabolism and excretion are subject to ongoing research. As with many antiviral agents, the development of resistance is a critical consideration, and studies are being conducted to evaluate the potential for resistance mutations. Overall, Radalbuvir represents a significant advancement in the search for effective therapies against HCV, contributing to the broader landscape of antiviral drug development.

Formula: C₃₀H₄₁NO₆S

InChI: InChI=1S/C30H41NO6S/c1-20-5-7-21(8-6-20)27(32)31(25-17-24(11-13-29(2,3)4)38-26(25)28(33)34)22-9-14-30(35,15-10-22)19-37-23-12-16-36-18-23/h5,17,21-23,35H,6-10,12,14-16,18-19H2,1-4H3,(H,33,34)/t21-,22-,23-,30+/m0/s1

InChI key: InChIKey=MUICUPWICXUNRS-GDCCIXDYSA-N

SMILES: N(C(=O)[C@@H]1CCC(C)=CC1)(C2=C(C(O)=O)SC(C#CC(C)(C)C)=C2)[C@H]3CC[C@@](CO[C@H]4CCOC4)(O)CC3

Synonyms:

• Radalbuvir
• GS 9669
• 2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[[cis-4-hydroxy-4-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]cyclohexyl][[(1R)-4-methyl-3-cyclohexen-1-yl]carbonyl]amino]-
• 5-(3,3-Dimethyl-1-butyn-1-yl)-3-[[cis-4-hydroxy-4-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]cyclohexyl][[(1R)-4-methyl-3-cyclohexen-1-yl]carbonyl]amino]-2-thiophenecarboxylic acid

Radalbuvir

CAS: 1314795-11-3

Radalbuvir (GS-9669) is an investigational antiviral agent for the treatment of hepatitis C virus (HCV) infection as an NS5B inhibitor.

Formula: C₃₀H₄₁NO₆S

Color and Shape: Solid

Molecular weight: 543.71

Ref: TM-T34254