CAS 1314883-11-8

MMV-390048

Description:

MMV-390048, with the CAS number 1314883-11-8, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential as an antimalarial agent. It belongs to a class of compounds known as imidazolopiperazines, which are characterized by their unique bicyclic structure. This compound exhibits potent activity against Plasmodium falciparum, the parasite responsible for the most severe form of malaria. MMV-390048 operates through a mechanism that disrupts the parasite's ability to replicate and survive within the host. Its pharmacological profile suggests favorable properties, including good solubility and metabolic stability, which are essential for effective drug development. Additionally, MMV-390048 has been evaluated for its safety and efficacy in preclinical studies, showing promise as a candidate for further development in the fight against malaria. Ongoing research aims to optimize its properties and assess its potential in clinical settings, contributing to the global effort to combat malaria and improve treatment options.

Formula: C₁₈H₁₄F₃N₃O₂S

Synonyms:

• MMV-390048,inhibit,PI4 kinases,Parasite,Inhibitor,MMV390048,MMV 390048,Phosphatidylinositol 4 kinases,PI4K
• MMV-390048
• [3,3'-Bipyridin]-2-amine, 5-[4-(methylsulfonyl)phenyl]-6'-(trifluoromethyl)-
• MMV 048

MMV390048

CAS: 1314883-11-8

MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM).

Formula: C₁₈H₁₄F₃N₃O₂S

Purity: 97.48%

Color and Shape: Solid

Molecular weight: 393.38

Ref: TM-T16125

MMV-390048

CAS: 1314883-11-8

Formula: C₁₈H₁₄F₃N₃O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 393.3829

Ref: IN-DA01FKZ6

MMV390048

CAS: 1314883-11-8

MMV390048

Purity: ≥95%

Molecular weight: 393.38g/mol

Ref: 54-BUP05510