CAS 1315355-92-0

Mal-amido-PEG5-C2-NHS ester

Description:

Mal-amido-PEG5-C2-NHS ester is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives, which are widely used in bioconjugation and drug delivery applications. This compound features a malonic amide functional group, which enhances its reactivity and allows for the conjugation with various biomolecules, such as proteins or peptides. The PEG segment provides hydrophilicity, improving solubility and biocompatibility, while the NHS (N-hydroxysuccinimide) ester moiety facilitates the formation of stable amide bonds with primary amines in target molecules. The presence of a two-carbon (C2) linker contributes to the flexibility and spatial arrangement of the conjugated entities. Overall, Mal-amido-PEG5-C2-NHS ester is characterized by its ability to form stable conjugates, making it a valuable tool in the fields of biochemistry and pharmaceutical research for targeted drug delivery and the development of bioconjugates.

Formula: C₂₄H₃₅N₃O₁₂

Synonyms:

• 4,7,10,13,16-Pentaoxa-19-azadocosanoic acid, 22-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-20-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
• Mal-amido-PEG5-C2-?NHS ester

4,7,10,13,16-Pentaoxa-19-azadocosanoic acid, 22-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-20-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

CAS: 1315355-92-0

Formula: C₂₄H₃₅N₃O₁₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 557.5476

Ref: IN-DA000ZD6

Mal-amido-PEG5-C2-​NHS ester

CAS: 1315355-92-0

Mal-amido-PEG5-C2-​NHS ester

Purity: 98%

Molecular weight: 557.55g/mol

Ref: 54-OR1033807

Mal-amido-PEG5-C2-​NHS ester

CAS: 1315355-92-0

Mal-amido-PEG10-C2-NHS ester: noncleavable ADC linker with maleimide, NHS ester for labeling -NH2 in proteins/oligonucleotides.

Formula: C₂₄H₃₅N₃O₁₂

Color and Shape: Solid

Molecular weight: 557.55

Ref: TM-T18243

2,5-DIOXOPYRROLIDIN-1-YL 1-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)-3-OXO-7,10,13,16,19-PENTAOXA-4-AZADOCOSAN-22-OATE

CAS: 1315355-92-0

Purity: 98%

Molecular weight: 557.5529785

Ref: 10-F828130

Mal-amido-PEG5-C2-​NHS ester

CAS: 1315355-92-0

Mal-amido-PEG5-C2-​NHS ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Mal-amido-PEG5-C2-​NHS ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₂₄H₃₅N₃O₁₂

Purity: Min. 95%

Molecular weight: 557.5 g/mol

Ref: 3D-QCC35592