CAS 1315378-69-8

pep2-AVKI

CAS: 1315378-69-8

Peptide inhibits GluA2's binding to PICK1; doesn't alter GRIP/ABP binding, AMPA current, or LTD.

Formula: C₆₀H₉₃N₁₃O₁₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 1268.47

Ref: TM-TP1942

pep2-AVKI

CAS: 1315378-69-8

Pep2-AVKI is a potent postsynaptic potential (PSP) agonist. It is a potentiator of synaptic transmission at glutamatergic synapses, and enhances the amplitude of the PSPs induced by dopamine, glutamate, or acetylcholine in hippocampal CA1 neurons. Pep2-AVKI also interacts with cytosolic proteins that have been shown to be involved in the potentiation of synaptic transmission. These interactions are required for its efficacy as a potentiator of synaptic transmission. Pep2-AVKI has been shown to be efficacious in animal models of autoimmune diseases and may work through its ability to modulate immune responses.

Formula: C₆₀H₉₃N₁₃O₁₇

Purity: Min. 95%

Molecular weight: 1,268.5 g/mol

Ref: 3D-QCC37869