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CAS 131570-57-5

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Boc-D-Dab(Fmoc)-OH

Description:
Boc-D-Dab(Fmoc)-OH, with the CAS number 131570-57-5, is a protected amino acid derivative commonly used in peptide synthesis. It features a Boc (tert-butyloxycarbonyl) protecting group on the amino group and an Fmoc (9-fluorenylmethoxycarbonyl) protecting group on the side chain of the amino acid. This compound is characterized by its stability under basic conditions, making it suitable for various synthetic applications. The presence of both Boc and Fmoc groups allows for selective deprotection steps, facilitating the synthesis of complex peptides. The D-Dab (D-2,4-diaminobutyric acid) structure contributes to its unique properties, including the ability to introduce cationic charges into peptides, which can enhance solubility and biological activity. Additionally, Boc-D-Dab(Fmoc)-OH is typically white to off-white in appearance and is soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO). Its applications extend to drug development and the study of peptide interactions in biological systems.
Formula:C24H28N2O6
InChI:InChI=1/C24H28N2O6/c1-24(2,3)32-23(30)26-20(21(27)28)12-13-25-22(29)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m1/s1
SMILES:CC(C)(C)OC(=N[C@H](CCN=C(O)OCC1c2ccccc2c2ccccc12)C(=O)O)O
Synonyms:
  • (2R)-2-(tert-butoxycarbonylamino)-4-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid
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