CAS 1316059-00-3

GSK854

CAS: 1316059-00-3

GSK854

Purity: ≥98%

Molecular weight: 482.96g/mol

Ref: 54-BUP07295

GSK 854

CAS: 1316059-00-3

Molecular probe for understanding the biology of troponin I-interacting kinase (TNNI3K) and its role in heart failure. The compound exhibits substantial selectivity for TNNI3K over homologous kinases B-Raf and EGFR. In vivo studies showed reduced ROS and p38 MAP kinase activation in mice models for myocardial infarction resulting in reduced left ventricular dysfunction and improved remodelling.

Formula: C₁₈H₁₉ClN₆O₄S₂

Purity: Min. 95%

Molecular weight: 482.97 g/mol

Ref: 3D-BG165704

GSK854

CAS: 1316059-00-3

GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.

Formula: C₁₈H₁₉ClN₆O₄S₂

Purity: 98.91%

Color and Shape: Solid

Molecular weight: 482.96

Ref: TM-T24115