CAS 1316303-44-2
:Artesunate-d3
Description:
Artesunate-d3 is a deuterated derivative of artesunate, which is an antimalarial compound derived from artemisinin, a natural product extracted from the sweet wormwood plant (Artemisia annua). The "d3" designation indicates that this compound contains three deuterium atoms, which are isotopes of hydrogen, replacing regular hydrogen atoms in the molecular structure. This modification is often used in research to trace metabolic pathways or to improve the pharmacokinetic properties of the drug. Artesunate itself is known for its rapid action against Plasmodium parasites, particularly in treating severe malaria. The deuterated form may exhibit altered solubility, stability, and bioavailability compared to its non-deuterated counterpart. As with other antimalarials, the mechanism of action involves the generation of reactive oxygen species that damage the parasite's cellular components. Artesunate-d3 is primarily utilized in scientific research rather than clinical applications, providing insights into the drug's behavior in biological systems.
Formula:C19H28O8
InChI:InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1/i2D3
InChI key:InChIKey=FIHJKUPKCHIPAT-XJCJQZEVSA-N
SMILES:C([C@@H]1[C@]2([C@]34[C@](O[C@H]1OC(CCC(O)=O)=O)(O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])[H])[H])([2H])([2H])[2H]
Synonyms:- Artesunate-d3
- Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-triMethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester-d3
- Artesunic Acid-d3
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Found 2 products.
Artesunate-d3
CAS:Please enquire for more information about Artesunate-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C19H27O8Purity:Min. 95%Molecular weight:386.4 g/mol
