CAS 131707-23-8

Arbidol

Description:

Arbidol, also known by its chemical name umifenovir, is an antiviral medication primarily used for the prevention and treatment of influenza and other viral infections. It is characterized by its ability to inhibit viral replication and enhance the immune response. Arbidol functions by blocking the fusion of the viral envelope with the host cell membrane, thereby preventing the entry of the virus into the cell. The substance is classified as a small molecule and has a relatively low molecular weight. It is typically administered orally and is known for its favorable safety profile, with minimal side effects reported. Arbidol has been studied for its potential efficacy against various viruses, including coronaviruses, and has garnered attention during outbreaks. Its mechanism of action, along with its pharmacokinetic properties, makes it a subject of interest in antiviral research. However, its use and approval can vary by country, reflecting differing regulatory perspectives on its effectiveness and application in clinical settings.

Formula: C₂₂H₂₅BrN₂O₃S·ClH

InChI: InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;/h6-11,26H,5,12-13H2,1-4H3;1H

InChI key: InChIKey=OMZHXQXQJGCSKN-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C=2C(N(C)C1CSC3=CC=CC=C3)=CC(Br)=C(O)C2CN(C)C.Cl

Synonyms:

• 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, hydrochloride (1:1)
• 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, monohydrochloride
• 6-Bromo-4-[(Dimethylamino)Methyl]-5-Hydroxy-1-Methyl-2-[(Phenylthio)Methyl]-1H-Indole-3-Carboxylic Acid Ethyl Ester Monohydrochloride
• Arbidol
• Arbidol hydrochloride
• Arbidolhydrochloride
• Umifenovir hydrochloride
• ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate hydrochloride
• ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate hydrochloride hydrate

Arbidol Hydrochloride

CAS: 131707-23-8

Formula: C₂₂H₂₅BrN₂O₃S·HCl

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 513.88

Ref: 3B-A3402

Umifenovir hydrochloride

CAS: 131707-23-8

Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with

Formula: C₂₂H₂₅BrN₂O₃S·HCl

Purity: 99.36% - 99.88%

Color and Shape: White Or Off-White Crystalline Powder

Molecular weight: 513.88

Ref: TM-T0104

1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, hydrochloride (1:1)

CAS: 131707-23-8

Formula: C₂₂H₂₆BrClN₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 513.8754

Ref: IN-DA000ZLV

Arbidol HCl

CAS: 131707-23-8

Formula: C₂₂H₂₅BrN₂O₃S·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 477.42 36.46

Ref: 4Z-A-116001

Umifenovir hydrochloride

CAS: 131707-23-8

Purity: ≥ 98.0%

Color and Shape: White to beige powder

Ref: 7W-GW1024

Arbidol-d6 Hydrochloride

Controlled Product

CAS: 131707-23-8

Formula: C₂₂H₂₀D₆BrClN₂O₃S

Color and Shape: Neat

Molecular weight: 519.91

Ref: TR-A766002

Arbidol Hydrochloride

CAS: 131707-23-8

Stability Hygroscopic
Applications A medicinal agent for treating viral infections.
References Chiou, W., et al.: J. Pharm. Sci., 60, 1281 (1971), Ford, J., et al.: J. Pharm. Pharmacol., 31, 726 (1979), Tamblyn, S., et al.: Eur. J. Epidemiol., 10, 503 (1994), Suzuki, H., et al.: Chem. Pharm. Bull., 45, 1688 (1997),

Formula: C₂₂H₂₅BrN₂O₃S·ClH

Color and Shape: Neat

Molecular weight: 513.88

Ref: TR-A766000

Umifenovir hydrochloride

Controlled Product

CAS: 131707-23-8

Arbidol is an antiviral molecule that acts by blocking endocytosis and the replication steps of infection. As a drug, arbidol has been suggested in the prophylaxis of SARS-CoV-2 infection.

Formula: C₂₂H₂₆BrClN₂O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 513.88 g/mol

Ref: 3D-FA17969

Arbidol Hydrochloride

CAS: 131707-23-8

Formula: C₂₂H₂₅BrN₂O₃SHCl

Molecular weight: 477.42 : 36.46

Ref: ST-EA-CP-A246018