CAS 131747-54-1

2-BROMO-3-(HYDROXYMETHYL)PYRIDINE

Description:

2-Bromo-3-(hydroxymethyl)pyridine is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of a bromine atom at the second position and a hydroxymethyl group (-CH2OH) at the third position of the pyridine ring defines its structure and reactivity. This compound is typically a colorless to pale yellow liquid or solid, depending on its form and purity. It is soluble in polar solvents, such as water and alcohols, due to the hydroxymethyl group, which can engage in hydrogen bonding. The bromine substituent can participate in nucleophilic substitution reactions, making this compound useful in various synthetic applications, including medicinal chemistry and the development of pharmaceuticals. Additionally, the hydroxymethyl group can serve as a functional handle for further chemical modifications. Safety precautions should be observed when handling this compound, as it may pose health risks, including irritation or toxicity.

Formula: C₆H₆BrNO

InChI: InChI=1/C6H6BrNO/c7-6-5(4-9)2-1-3-8-6/h1-3,9H,4H2

SMILES: c1cc(CO)c(Br)nc1

Synonyms:

• (2-Bromo-Pyridin-3-Yl)-Methanol
• 2-Bromonicotinyl Alcohol
• 2-Bromo-3-Pyridinemethanol

2-Bromo-3-pyridinemethanol

CAS: 131747-54-1

Formula: C₆H₆BrNO

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 188.02

Ref: 3B-B2674

3-Pyridinemethanol, 2-bromo-

CAS: 131747-54-1

Formula: C₆H₆BrNO

Purity: 95%

Color and Shape: Solid

Molecular weight: 188.0219

Ref: IN-DA000ZOG

(2-Bromo-3-pyridyl)methanol

CAS: 131747-54-1

(2-Bromo-3-pyridyl)methanol

Purity: 98%

Molecular weight: 188.02g/mol

Ref: 54-OR480253

(2-Bromopyridin-3-yl)methanol

CAS: 131747-54-1

Formula: C₆H₆BrNO

Purity: 98%

Color and Shape: Solid, White to slightly pale yellow powder

Molecular weight: 188.024

Ref: 10-F222366

2-Bromo-3-pyridinemethanol

CAS: 131747-54-1

2-Bromo-3-pyridinemethanol is a heteroaryl compound that contains a pyridine ring. It is synthesized by the lithiation of 2-bromopyridine followed by intramolecular bromination with 3-bromopyridinemethanol. The methodologies for this synthesis are similar to those used in the synthesis of quinolines and pyridines. Lithiation of 2-bromopyridine at low temperature (0°C) led to the formation of 2,6-dibromopyridine, which was then reacted with 3-bromopyridinemethanol in a sequence similar to that described for the synthesis of quinoline and pyridine. This reaction yielded 2,6-dibromo-3-(2'-pyridinyl)-N,N'-dimethylethanamine. The desired product was obtained after cyclization with potassium tert

Formula: C₆H₆BrNO

Purity: Min. 95%

Molecular weight: 188.02 g/mol

Ref: 3D-GFA74754