CAS 131780-47-7

8-METHYL-8-AZABICYCLO-3-ENDO[3.2.1]OCT-3-YL-1,4-DIHYDRO-2-OXO-3(2H)-QUINAZOLINECARBOXYLIC ACID ESTER HYDROCHLORIDE

Description:

8-Methyl-8-azabicyclo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride is a complex organic compound characterized by its bicyclic structure, which includes a nitrogen atom in the ring system, contributing to its azabicyclic nature. The presence of a quinazoline moiety indicates potential biological activity, as quinazolines are known for their pharmacological properties. This compound features a dihydro-2-oxo group, suggesting it may exhibit reactivity typical of carbonyl-containing compounds. The hydrochloride salt form indicates enhanced solubility in aqueous environments, which is often advantageous for biological assays and pharmaceutical applications. Its structural complexity may contribute to unique interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the methyl group at the 8-position may influence the compound's lipophilicity and overall pharmacokinetic profile. Overall, this compound's intricate structure and functional groups suggest potential utility in drug development, particularly in areas targeting neurological or other disorders.

Formula: C₁₇H₂₂ClN₃O₃

InChI: InChI=1/C17H21N3O3.ClH/c1-19-12-6-7-13(19)9-14(8-12)23-17(22)20-10-11-4-2-3-5-15(11)18-16(20)21;/h2-5,12-14H,6-10H2,1H3,(H,18,21);1H/t12-,13+,14+;

Synonyms:

• Dau 5884 Hydrochloride
• [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride

3(2H)-Quinazolinecarboxylic acid, 1,4-dihydro-2-oxo-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

CAS: 131780-47-7

Formula: C₁₇H₂₁N₃O₃

Color and Shape: Solid

Molecular weight: 315.3669

Ref: IN-DA000ZQ5

DAU-5884

CAS: 131780-47-7

DAU-5884 is a dopamine derivative that has potent anti-pertussis effects. It is also a nutritional supplement and can be used in the treatment of aerobic gram-negative bacterial infections, such as Bordetella pertussis. DAU-5884 is an inhibitor of bacterial fatty acid synthesis, which blocks the production of fatty acids necessary for growth. This inhibition has been shown to be bactericidal against the type strain of Bordetella pertussis. DAU-5884 can be effective against other types of bacteria as well, including Escherichia coli and Pseudomonas aeruginosa. DAU-5884 inhibits guanine synthesis by blocking the enzyme ribonucleotide reductase. This drug also blocks protein synthesis by inhibiting amino acid transport into the cell and preventing protein translocation from within the cytoplasm to the ribosomes on the cell membrane or inner membrane surface.

Formula: C₁₇H₂₁N₃O₃

Purity: Min. 95%

Molecular weight: 315.37 g/mol

Ref: 3D-GFA78047

DAU 5884 HCl

CAS: 131780-47-7

DAU 5884 HCl is an M3 receptor antagonist

Formula: C₁₇H₂₁N₃O₃

Color and Shape: Solid

Molecular weight: 315.37

Ref: TM-T71962