CymitQuimica logo

CAS 131791-98-5

:

Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)

Description:
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a synthetic peptide derived from hirudin, a naturally occurring anticoagulant protein found in leeches. This compound is characterized by its specific amino acid sequence, which includes a succinyl modification at the N-terminus and a sulfate group that enhances its anticoagulant properties. The presence of D-glutamic acid at position 65 contributes to its stability and biological activity. Hirudin and its derivatives are known for their ability to inhibit thrombin, a key enzyme in the coagulation cascade, making them valuable in therapeutic applications for preventing thrombosis. The sulfation of this peptide increases its negative charge, potentially enhancing its interaction with positively charged sites on thrombin. This modification can also influence its solubility and pharmacokinetics. Overall, Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) represents a tailored approach to developing anticoagulant agents with improved efficacy and specificity in clinical settings.
Formula:C64H88N10O26S
Synonyms:
  • Suc-Phe-Glu-Pro-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-D-Glu-OH
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.