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CAS 13182-82-6

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Metronidazole acetate

Description:
Metronidazole acetate, with the CAS number 13182-82-6, is a derivative of metronidazole, an antibiotic commonly used to treat various infections, particularly those caused by anaerobic bacteria and protozoa. This compound typically appears as a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and methanol, but has limited solubility in water. The acetate moiety enhances its pharmacokinetic properties, potentially improving absorption and bioavailability. Metronidazole acetate retains the antimicrobial activity of its parent compound, making it effective against a range of pathogens. It is important to note that, like other nitroimidazole derivatives, it may exhibit side effects, including gastrointestinal disturbances and potential neurotoxicity with prolonged use. The compound's mechanism of action involves the reduction of its nitro group, leading to the formation of reactive intermediates that damage bacterial DNA. As with any pharmaceutical, its use should be guided by appropriate medical advice and consideration of resistance patterns in target pathogens.
Formula:C8H11N3O4
InChI:InChI=1S/C8H11N3O4/c1-6-9-5-8(11(13)14)10(6)3-4-15-7(2)12/h5H,3-4H2,1-2H3
InChI key:InChIKey=MQXDTGGRMOLAPU-UHFFFAOYSA-N
SMILES:C(COC(C)=O)N1C(N(=O)=O)=CN=C1C
Synonyms:
  • 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-, 1-acetate
  • 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-, acetate (ester)
  • 2-Methyl-5-nitro-1H-imidazole-1-ethanol acetate (ester)
  • Imidazole-1-ethanol, 2-methyl-5-nitro-, acetate
  • Imidazole-1-ethanol, 2-methyl-5-nitro-, acetate (ester)
  • Metronidazole acetate
  • O-Acetylmetronidazole
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Found 2 products.
  • O-Acetylmetronidazole
    Mikromol
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    O-Acetylmetronidazole

    CAS:
    Color and Shape:Neat

    Ref: 86-MM0012.11

    25mg
    To inquire
  • Metronidazole Acetate
    TRC
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    Metronidazole Acetate

    Controlled Product
    CAS:
    <p>Applications Metronidazole Acetate is a protected Metronidazole (M338880). Metronidazole Acetate is an imidazole derivative with anti-trichomonas, antifungal and spermicidal activity.<br>References Kumar, L. et al.: ACS Med. Chem. Lett., 3, 83 (2012); Kumar, L. et al.: Eur. J. Med. Chem., 45, 817 (2010)<br></p>
    Formula:C8H11N3O4
    Color and Shape:Neat
    Molecular weight:213.19

    Ref: TR-M338885

    10mg
    263.00€
    100mg
    1,712.00€