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CAS 131875-08-6

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Lexacalcitol

Description:
Lexacalcitol is a synthetic analog of calcitriol, the active form of vitamin D, primarily used in the treatment of conditions related to calcium metabolism, such as osteoporosis and secondary hyperparathyroidism. It is characterized by its ability to bind to vitamin D receptors, thereby influencing calcium and phosphate homeostasis in the body. Lexacalcitol promotes intestinal absorption of calcium, enhances renal tubular reabsorption of calcium, and inhibits parathyroid hormone secretion, contributing to its therapeutic effects. The substance is typically administered in a pharmaceutical form, and its efficacy is often evaluated through its impact on bone density and mineral metabolism. Lexacalcitol is known for its relatively high potency compared to other vitamin D analogs, which allows for lower dosing regimens. Additionally, it has a favorable safety profile, although potential side effects may include hypercalcemia and hyperphosphatemia if not monitored properly. Overall, Lexacalcitol represents an important option in the management of disorders associated with vitamin D deficiency and calcium imbalance.
Formula:C29H48O4
InChI:InChI=1S/C29H48O4/c1-6-29(32,7-2)16-9-17-33-21(4)25-13-14-26-22(10-8-15-28(25,26)5)11-12-23-18-24(30)19-27(31)20(23)3/h11-12,21,24-27,30-32H,3,6-10,13-19H2,1-2,4-5H3/b22-11+,23-12-/t21-,24-,25-,26+,27+,28-/m1/s1
InChI key:InChIKey=KLZOTDOJMRMLDX-YBBVPDDNSA-N
SMILES:C[C@@]12[C@](\C(=C\C=C\3/C(=C)[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@H](OCCCC(CC)(CC)O)C)[H])[H]
Synonyms:
  • (1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-Ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
  • (1S,3R,5Z,7E,9xi,20R)-20-[(4-ethyl-4-hydroxyhexyl)oxy]-9,10-secopregna-5,7,10-triene-1,3-diol
  • (5Z,7E,20R)-20-[(4-Ethyl-4-hydroxyhexyl)oxy]-9,10-secopregna-5,7,10(19)-triene-1α,3β-diol
  • 1,3-Cyclohexanediol, 5-[(2E)-2-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-
  • 1,3-Cyclohexanediol, 5-[(2E)-[(1S,3aS,7aS)-1-[(1R)-1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-
  • 1,3-Cyclohexanediol, 5-[[1-[1-[(4-ethyl-4-hydroxyhexyl)oxy]ethyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, [1S-[1α(S*),3aβ,4E(1S*,3R*,5Z),7aα]]-
  • Kh 106
  • Kh 1060
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Found 3 products.
  • Lexacalcitol
    Indagoo
    + Info

    Lexacalcitol

    CAS:
    Formula:C29H48O4
    Purity:99.42%
    Molecular weight:460.6890

    Ref: IN-DA009CCP

    1mg
    To inquire
    5mg
    To inquire
  • Lexacalcitol
    Targetmol
    + Info

    Lexacalcitol

    CAS:
    <p>Lexacalcitol is a potent compound, 100x more effective than 1alpha,25-(OH)2D3 in antiproliferation and cell differentiation tests.</p>
    Formula:C29H48O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:460.69

    Ref: TM-T15745

  • Lexacalcitol
    TRC
    + Info

    Lexacalcitol

    Controlled Product
    CAS:
    Formula:C29H48O4
    Color and Shape:Neat
    Molecular weight:460.689

    Ref: TR-L397700

    10mg
    30,850.00€