CAS 131933-18-1

2-(2-cyclohexylethoxy)adenosine

Description:

2-(2-Cyclohexylethoxy)adenosine, with the CAS number 131933-18-1, is a modified nucleoside derivative of adenosine. This compound features a cyclohexyl group attached to an ethoxy chain, which is linked to the adenosine structure. The presence of the cyclohexyl moiety contributes to its lipophilicity, potentially enhancing its ability to cross biological membranes. As a nucleoside analog, it may exhibit biological activity, particularly in relation to adenosine receptors, which are involved in various physiological processes including neurotransmission, immune response, and cardiovascular function. The modification of the adenosine structure can influence its binding affinity and selectivity for these receptors, making it a subject of interest in pharmacological research. Additionally, the compound's solubility, stability, and reactivity can be affected by the cyclohexyl and ethoxy substituents, which may also play a role in its therapeutic potential. Overall, 2-(2-cyclohexylethoxy)adenosine represents a significant area of study in medicinal chemistry and drug development.

Formula: C₁₈H₂₇N₅O₅

InChI: InChI=1/C18H27N5O5/c19-15-12-16(22-18(21-15)27-7-6-10-4-2-1-3-5-10)23(9-20-12)17-14(26)13(25)11(8-24)28-17/h9-11,13-14,17,24-26H,1-8H2,(H2,19,21,22)/t11-,13-,14-,17-/m1/s1

SMILES: C1CCC(CC1)CCOc1nc(c2c(n1)n(cn2)[C@H]1[C@@H]([C@@H]([C@@H](CO)O1)O)O)N

Synonyms:

• Wrc 0013
• Sha 91
• Adenosine, 2-(2-cyclohexylethoxy)-
• 2-(2-Cyclohexylethoxy)adenosine

2-(2-Cyclohexylethoxy)adenosine

CAS: 131933-18-1

Ref: 7W-GN2747

2-(2-Cyclohexylethoxy)adenosine

CAS: 131933-18-1

2-(2-Cyclohexylethoxy)adenosine (CX-5461) is a new chemical entity that has been shown to have an incremental effect on muscle contraction. The mechanism of action of CX-5461 is not fully understood, but it has been shown to be nonselective and to bind to adenosine receptors. This binding produces a response in the cell similar to that of adenosine, which is a small molecule involved in the regulation of blood pressure and heart rate. CX-5461 also binds with platelet membranes at the site of inflammation and causes vasodilation. It has been shown to be effective in animal models of pertussis, where it reduces the severity of muscle spasms and increases the duration before death. These effects are due to CX-5461's ability to lower intracellular calcium concentrations by preventing calcium release from internal stores or from outside sources such as muscle cells or platelets.

Formula: C₁₈H₂₇N₅O₅

Purity: Min. 95%

Molecular weight: 393.44 g/mol

Ref: 3D-NC16523