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CAS 131986-45-3

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Xanomeline

Description:
Xanomeline is a synthetic compound primarily recognized for its role as a muscarinic acetylcholine receptor agonist. It is characterized by its ability to selectively activate certain subtypes of muscarinic receptors, particularly M1 and M4, which are implicated in cognitive functions and the modulation of neurotransmitter release. This selectivity makes xanomeline of interest in the treatment of conditions such as Alzheimer's disease and schizophrenia, as it may enhance cognitive function and reduce symptoms associated with these disorders. The compound is typically administered in the form of its hydrochloride salt, which enhances its solubility and bioavailability. Xanomeline has been studied for its potential to improve cognitive deficits without the side effects commonly associated with traditional antipsychotic medications. Its pharmacological profile suggests a lower propensity for causing extrapyramidal symptoms, making it a candidate for further research in neuropsychiatric applications. However, as with any pharmacological agent, the safety, efficacy, and long-term effects of xanomeline require thorough investigation through clinical trials.
Formula:C14H23N3OS
InChI:InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
InChI key:InChIKey=JOLJIIDDOBNFHW-UHFFFAOYSA-N
SMILES:O(CCCCCC)C=1C(=NSN1)C=2CN(C)CCC2
Synonyms:
  • 1,2,5-Thiadiazole, pyridine deriv.
  • 3-Hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
  • 3-[4-(Hexy loxy)-1,2,5-thiadiazol-3-y1]-1,2,5,6-tetrahydro-1-methylpyridine
  • 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine
  • Lomeron
  • Ly-246708
  • Memcor
  • Nnc-11-0232
  • Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-
  • Xanomeline
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Found 6 products.