CAS 131986-45-3

Xanomeline

Description:

Xanomeline is a synthetic compound primarily recognized for its role as a muscarinic acetylcholine receptor agonist. It is characterized by its ability to selectively activate certain subtypes of muscarinic receptors, particularly M1 and M4, which are implicated in cognitive functions and the modulation of neurotransmitter release. This selectivity makes xanomeline of interest in the treatment of conditions such as Alzheimer's disease and schizophrenia, as it may enhance cognitive function and reduce symptoms associated with these disorders. The compound is typically administered in the form of its hydrochloride salt, which enhances its solubility and bioavailability. Xanomeline has been studied for its potential to improve cognitive deficits without the side effects commonly associated with traditional antipsychotic medications. Its pharmacological profile suggests a lower propensity for causing extrapyramidal symptoms, making it a candidate for further research in neuropsychiatric applications. However, as with any pharmacological agent, the safety, efficacy, and long-term effects of xanomeline require thorough investigation through clinical trials.

Formula: C₁₄H₂₃N₃OS

InChI: InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3

InChI key: InChIKey=JOLJIIDDOBNFHW-UHFFFAOYSA-N

SMILES: O(CCCCCC)C=1C(=NSN1)C=2CN(C)CCC2

Synonyms:

• 1,2,5-Thiadiazole, pyridine deriv.
• 3-Hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
• 3-[4-(Hexy loxy)-1,2,5-thiadiazol-3-y1]-1,2,5,6-tetrahydro-1-methylpyridine
• 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine
• Lomeron
• Ly-246708
• Memcor
• Nnc-11-0232
• Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-
• Xanomeline

Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-

CAS: 131986-45-3

Formula: C₁₄H₂₃N₃OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 281.4169

Ref: IN-DA00100T

Xanomeline

CAS: 131986-45-3

Xanomeline

Purity: ≥98%

Molecular weight: 281.42g/mol

Ref: 54-BUP06441

Xanomeline

CAS: 131986-45-3

Formula: C₁₄H₂₃N₃OS

Molecular weight: 281.42

Ref: 4Z-X-009001

Xanomeline

CAS: 131986-45-3

Formula: C₁₄H₂₃N₃OS

Molecular weight: 281.42

Ref: 7W-GP2978

3-(Hexyloxy)-4-(1-Methyl-1,2,5,6-Tetrahydropyridin-3-Yl)-1,2,5-Thiadiazole

Controlled Product

CAS: 131986-45-3

Formula: C₁₄H₂₃N₃OS

Color and Shape: Neat

Molecular weight: 281.417

Ref: TR-H298183

Xanomeline

CAS: 131986-45-3

Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.

Formula: C₁₄H₂₃N₃OS

Purity: 99.61%

Color and Shape: Solid

Molecular weight: 281.42

Ref: TM-T36640