CAS 132-22-9

(±)-Chlorpheniramine

Description:

(±)-Chlorpheniramine, with the CAS number 132-22-9, is an antihistamine commonly used to relieve symptoms of allergy, hay fever, and the common cold. It belongs to the class of first-generation antihistamines, which are known for their ability to cross the blood-brain barrier, often leading to sedative effects. The compound is characterized by its ability to selectively block H1 histamine receptors, thereby reducing the effects of histamine in the body, such as itching, sneezing, and runny nose. Chlorpheniramine is typically administered orally and is available in various formulations, including tablets and syrups. Its chemical structure features a chlorinated phenyl ring, contributing to its pharmacological activity. While effective for symptom relief, it may also cause side effects such as drowsiness, dry mouth, and dizziness. Due to its sedative properties, caution is advised when operating machinery or driving after consumption. Overall, (±)-Chlorpheniramine is a widely used medication in the treatment of allergic reactions and respiratory conditions.

Formula: C₁₆H₁₉ClN₂

InChI: InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3

InChI key: InChIKey=SOYKEARSMXGVTM-UHFFFAOYSA-N

SMILES: C(CCN(C)C)(C1=CC=C(Cl)C=C1)C2=CC=CC=N2

Synonyms:

• (.+-.)-Chloropheniramine
• 1-(p-Chlorophenyl)-1-(2'-pyridyl)-3-(N,N-dimethylamino)-propane
• 1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane
• 2-Pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-
• 2-[p-Chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine
• 3-(4-Chlorophenyl)-3-(2-Pyridyl)Propyldimethylamine
• 3-(p-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine
• 4-Chloropheniramine
• Allergican
• Chlorophenylpyridamine
• Chloropheriamine
• Chloroprophenpyridamine
• Chlorphenamin
• Chlorpheniramine
• Chlorprophenpyridamine
• Clorfenamina
• Haynon
• PYRIDINE, 2-(3-AMINOPROP-1-YL)-, γ-(4-CHLOROPHENYL)-N,N-DIMETHYL-
• Pyridine, 2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]-
• RS-Chlorpheniramine
• [3-(4-Chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
• dl-1-(p-Chlorophenyl)-1-(2-pyridyl)-3-(dimethylamino)propane
• γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine

Chlorpheniramine

CAS: 132-22-9

Chlorpheniramine is an H1 anti-histamine agent for IgE-mediated inflammation that is commonly used for allergic diseases.

Formula: C₁₆H₁₉ClN₂

Color and Shape: Solid

Molecular weight: 274.79

Ref: TM-T60498

Chlorpheniramine

CAS: 132-22-9

Applications Chlorpheniramine is an intermediate used in the synthesis of (R)-(-)-Chlorpheniramine Maleate (C424306), which is the R-enantiomer of Chlorpheniramine (C424300). Antihistaminic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ishida, M., et al.: Int. J. Pharm., 359, 46 (2008), Moreno, R., et al.: Biomed. Chromatog., 24, 774 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₁₆H₁₉ClN₂

Color and Shape: Neat

Molecular weight: 274.79

Ref: TR-C424705

Brompheniramine EP Impurity A

CAS: 132-22-9

Formula: C₁₆H₁₉ClN₂

Molecular weight: 274.79

Ref: ST-EA-CP-B52001