CAS 132-98-9: phenoxymethylpenicillinic acid*potassium

Description:Phenoxymethylpenicillinic acid potassium, commonly known as penicillin V potassium, is a type of antibiotic belonging to the penicillin class. It is characterized by its beta-lactam structure, which is essential for its antibacterial activity. This compound is typically administered in its potassium salt form to enhance solubility and bioavailability. It exhibits a broad spectrum of activity against various Gram-positive bacteria and some Gram-negative bacteria, making it effective in treating infections such as streptococcal pharyngitis and skin infections. The mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Phenoxymethylpenicillinic acid potassium is generally well-tolerated, though it can cause allergic reactions in some individuals. It is important to note that resistance to penicillin has been observed, necessitating careful consideration of its use in clinical settings. The compound is usually administered orally and is stable in acidic environments, which contributes to its effectiveness in treating infections.

Formula:C₁₆H₁₈N₂O₅S·K

InChI:InChI=1S/C16H18N2O5S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/t11-,12+,14-;/m1./s1

InChI key:InChIKey=CHMFOCYVRGABAO-LQDWTQKMSA-N

SMILES:[K].O=C(O)C1N2C(=O)C(NC(=O)COC=3C=CC=CC3)C2SC1(C)C

Synonyms:
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Acipen
Anapenil
Antibiocin
Arcacil
Arcasin
Asillin
Beapen
Beromycin
Cilacil
See more synonyms
Cliacil
Dqv-K
DuraPenicillin
Fenocin
Fenospen
Fenoxcillin
Fenoxypen
Icipen
Isocillin
Ispenoral
Kavepenin
L.P.V.
Megacillin-oral
Milcopen
Newcillin
Orapen
Orvek
Ospeneff
P.V.O.
Pedipen
Pen-V
Pen-Vee-K
Pen-Vi-K
Penagen
Pencompren
Penivoral
Penoxilin
Pentabs
Pentacillin
Pentranex
Penvikal
Penvisil
Primcillin
Rocilin
Roscopenin
Suspen
Trepopen
V-Pen
Vamosyn
Veetids
Vepen
Vepicombin
phenoxymethylpenicillin potassium
potassium 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, monopotassium salt, [2S-(2α,5α,6β)]-
V-Cillin K
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, monopotassium salt, (2S,5R,6R)-
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, potassium salt (1:1), (2S,5R,6R)-
Penicillin V potassium salt
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-, monopotassium salt
Phenoxymethyl Penicillin Potassium
Penicillin V Potassium
Potassium V Penicillin
potassium penicillin V