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CAS 132036-88-5

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Ramosetron

Description:
Ramosetron is a selective serotonin 5-HT3 receptor antagonist primarily used in the management of nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. It is characterized by its ability to block the action of serotonin at the 5-HT3 receptors, which are located in the central nervous system and gastrointestinal tract. This action helps to mitigate the emetic response triggered by various stimuli. Ramosetron is known for its relatively long half-life, allowing for less frequent dosing compared to some other antiemetics. The compound is typically administered orally or intravenously, depending on the clinical scenario. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. While generally well-tolerated, potential side effects may include headache, constipation, and dizziness. As with any medication, its use should be guided by a healthcare professional, considering individual patient factors and potential drug interactions.
Formula:C17H17N3O
InChI:InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1
InChI key:InChIKey=NTHPAPBPFQJABD-LLVKDONJSA-N
SMILES:C(=O)(C=1C=2C(N(C)C1)=CC=CC2)[C@H]3CC4=C(CC3)N=CN4
Synonyms:
  • (-)-(R)-1-Methylindol-3-yl 4,5,6,7-tetrahydro-5-benzimidazolylketone
  • (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]methanone
  • (1-methyl-1H-indol-3-yl)[(6S)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]methanone
  • (R)-5-[(1-Methylindole-3-Yl)Carbonyl]-4,5,6,7-Tetrahydro-1H-Bezimidazole, 98+%
  • Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (R)-
  • Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]-
  • Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]- (9CI)
  • Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-
  • Nasea
  • Nor-YM 060
  • Ramosetron
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