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CAS 1321827-45-5

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  • SBI-0640726

    CAS:
    <p>SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation complex by inhibiting the AKT and NF-kB signaling pathways. Additionally, SBI-0640726 inhibits the growth of melanoma with NRAS and BRAF mutations in vitro.</p>
    Formula:C23H15ClN2O2
    Color and Shape:Solid
    Molecular weight:386.83