
CAS 1321827-45-5
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SBI-0640726
CAS:<p>SBI-0640726, an eIF4G1 inhibitor, exhibits antiproliferative activity against melanoma. It disrupts the eIF4F translation initiation complex by inhibiting the AKT and NF-kB signaling pathways. Additionally, SBI-0640726 inhibits the growth of melanoma with NRAS and BRAF mutations in vitro.</p>Formula:C23H15ClN2O2Color and Shape:SolidMolecular weight:386.83
