CAS 13220-57-0
:Tryptanthrin
Description:
Tryptanthrin is an indole alkaloid characterized by its unique bicyclic structure, which includes a fused indole and isoquinoline moiety. It is typically found in various plant species and has garnered interest due to its potential biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. Tryptanthrin is known for its ability to interact with various biological targets, making it a subject of research in pharmacology and medicinal chemistry. The compound is generally soluble in organic solvents but has limited solubility in water, which can influence its bioavailability and therapeutic applications. Its molecular formula reflects a specific arrangement of carbon, hydrogen, nitrogen, and oxygen atoms, contributing to its chemical reactivity and stability. Additionally, tryptanthrin's fluorescence properties make it useful in certain analytical applications. Overall, its diverse biological activities and unique chemical structure make tryptanthrin a compound of significant interest in both natural product chemistry and drug development.
Formula:C15H8N2O2
InChI:InChI=1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H
InChI key:InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N
SMILES:O=C1N2C(C(=O)C=3C2=CC=CC3)=NC=4C1=CC=CC4
Synonyms:- Couroupitine A
- Indolo(2,1-b)quinazoline-6,12-dione (8CI)(9CI)
- Indolo[2,1-B]Quinazoline-6,12-Dione
- Nsc 349447
- Triptantrin
- Tryptanthrine
- Tryptanthrin
- Tryptanthrin
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Found 11 products.
Indolo[2,1-b]quinazoline-6,12-dione
CAS:Formula:C15H8N2O2Purity:96%Color and Shape:SolidMolecular weight:248.2362Tryptanthrin
CAS:Formula:C15H8N2O2Purity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:248.24Tryptanthrin
CAS:<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Tryptanthrine
CAS:Natural alkaloidFormula:C15H8N2O2Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:248.24Tryptanthrin
CAS:<p>Applications Tryptanthrin is natural alkaloid, and a potent inhibitor of cyclooxygenase COX-2 and 5-lipoxygenase acting as an anti-inflammatory agent.<br>References Agafonova, I. et al.: App. Mag. Res., 46, 781 (2015);<br></p>Formula:C15H8N2O2Color and Shape:NeatMolecular weight:248.24Tryptanthrin
CAS:<p>Tryptanthrin is a natural compound that has been shown to inhibit the activity of P-glycoprotein (P-gp) by binding to its basic protein. Tryptanthrin has also been shown to be cytotoxic in bowel disease. Tryptanthrin has a significant cytotoxicity against HL60 cells, which is due to its ability to inhibit the activity of cyclin D2. This agent also inhibits the proliferation of HL60 cells induced by oxidative injury, and can be used as an anti-cancer therapeutic. Molecular docking analysis suggests that tryptanthrin binds with high affinity to the ATPase region of P-gp.</p>Formula:C15H8N2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:248.24 g/molTryptanthrin - Bio-X ™
CAS:<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C15H8N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:248.24 g/molIndolo[2,1-b]quinazoline-6,12-dione
CAS:Formula:C15H8N2O2Purity:97%Color and Shape:SolidMolecular weight:248.241
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