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CAS 132245-57-9

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Dexamethasone cipecilate

Description:
Dexamethasone cipecilate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a derivative of dexamethasone, which is widely used in the treatment of various conditions, including allergies, autoimmune diseases, and certain types of cancer. The substance is characterized by its ability to modulate the immune response and reduce inflammation by inhibiting the release of inflammatory mediators. Dexamethasone cipecilate is typically administered in a form that allows for enhanced bioavailability and prolonged action compared to its parent compound. Its pharmacological effects are primarily mediated through the glucocorticoid receptor, leading to alterations in gene expression that affect cellular processes. The compound is often evaluated for its efficacy in clinical settings, particularly in conditions requiring rapid and effective anti-inflammatory treatment. As with other corticosteroids, potential side effects may include metabolic changes, increased susceptibility to infections, and other systemic effects, necessitating careful monitoring during therapy.
Formula:C33H43FO7
InChI:InChI=1S/C33H43FO7/c1-19-15-25-24-12-11-22-16-23(35)13-14-30(22,2)32(24,34)26(36)17-31(25,3)33(19,41-29(39)21-9-10-21)27(37)18-40-28(38)20-7-5-4-6-8-20/h13-14,16,19-21,24-26,36H,4-12,15,17-18H2,1-3H3/t19-,24+,25+,26+,30+,31+,32+,33+/m1/s1
InChI key:InChIKey=JPTKVJWWVFLEJL-GVPGRCOTSA-N
SMILES:O(C(=O)C1CC1)[C@@]2(C(COC(=O)C3CCCCC3)=O)[C@]4(C)[C@@](C[C@H]2C)([C@]5([C@](F)([C@@H](O)C4)[C@]6(C)C(CC5)=CC(=O)C=C6)[H])[H]
Synonyms:
  • (11β,16α)-21-[(Cyclohexylcarbonyl)oxy]-17-[(cyclopropylcarbonyl)oxy]-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
  • Dexamethasone cipecilate
  • 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-cyclohexanecarboxylate 17-cyclopropanecarboxylate
  • Pregna-1,4-diene-3,20-dione, 21-[(cyclohexylcarbonyl)oxy]-17-[(cyclopropylcarbonyl)oxy]-9-fluoro-11-hydroxy-16-methyl-, (11β,16α)-
  • NS 126
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