CAS 1322544-82-0

Di-O-glycinoylcurcumin Dihydrochloride

Controlled Product

CAS: 1322544-82-0

Applications Di-O-glycinoylcurcumin Dihydrochloride is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers disea
References Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953), Tu, B., et al.: J .Cell Biol., 164, 341 (2004), Xu, G., et al.: Biochemistry, 44, 9817 (2005), Johnson, J., et al.: Cancer Lett., 255, 170 (2007), Chem. and Eng. News 90(31), 44 (2012)

Formula: C₂₅H₂₈Cl₂N₂O₈

Color and Shape: Neat

Molecular weight: 555.4

Ref: TR-D455700

Di-O-glycinoylcurcumin-d6 Dihydrochloride

Controlled Product

CAS: 1322544-82-0

Formula: C₂₅H₂₂D₆Cl₂N₂O₈

Color and Shape: Neat

Molecular weight: 488.519

Ref: TR-D455702

Di-o-glycinoylcurcumin-d6 dihydrochloride

CAS: 1322544-82-0

Di-o-glycinoylcurcumin-d6 dihydrochloride is an isotopically labeled curcumin derivative, which is a compound used primarily in biochemical and pharmaceutical research. This product is synthesized in the laboratory, with deuterium atoms incorporated strategically to facilitate NMR spectroscopy studies and other analytical applications.

Formula: C₂₅H₂₂D₆Cl₂N₂O₈

Purity: Min. 95%

Molecular weight: 561.44 g/mol

Ref: 3D-XCC54482