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CAS 132294-94-1

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DES (2-METHYLBUTYRATE) LOVASTATIN HYDROXY ACID SODIUM SALT

Description:
DES (2-Methylbutyrate) Lovastatin Hydroxy Acid Sodium Salt, with the CAS number 132294-94-1, is a sodium salt derivative of lovastatin, a naturally occurring statin used primarily for cholesterol management. This compound exhibits characteristics typical of statins, including the ability to inhibit HMG-CoA reductase, an enzyme crucial for cholesterol biosynthesis. As a sodium salt, it is likely to be more soluble in aqueous solutions compared to its parent compound, enhancing its bioavailability and therapeutic efficacy. The presence of the 2-methylbutyrate moiety may influence its pharmacokinetic properties, potentially affecting absorption, distribution, metabolism, and excretion. Additionally, this compound may exhibit anti-inflammatory and antioxidant properties, which are beneficial in cardiovascular health. Its safety profile is generally favorable, but like other statins, it may be associated with side effects such as muscle pain or liver enzyme elevation. Overall, DES Lovastatin Hydroxy Acid Sodium Salt represents a modified approach to cholesterol management, combining the benefits of lovastatin with improved solubility and potential bioactivity.
Formula:C19H29NaO5
InChI:InChI=1/C19H30O5.Na/c1-11-7-13-4-3-12(2)16(19(13)17(22)8-11)6-5-14(20)9-15(21)10-18(23)24;/h3-4,7,11-12,14-17,19-22H,5-6,8-10H2,1-2H3,(H,23,24);/q;+1/p-1/t11-,12-,14+,15+,16-,17-,19-;/m0./s1
SMILES:CC1C=C2C=CC(C)C(CCC(CC(CC(=O)O)O)O)C2C(C1)O.[Na]
Synonyms:
  • [1S-[1a(S*,dS*),2,6,8,8aa]]-1,2,6,7,8,8a-hexahydro-,d,8-trihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt
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