CAS 132295-44-4
:2,5-Anhydro-2,5-imino-D-glucitol
Description:
2,5-Anhydro-2,5-imino-D-glucitol, also known as "D-Glucitol, 2,5-anhydro-2,5-imino," is a chemical compound characterized by its unique structure that features both an anhydro and an imino group. This compound is a derivative of D-glucose and is notable for its potential applications in medicinal chemistry, particularly in the development of anti-diabetic agents. It is a white to off-white solid that is soluble in water, which is a common characteristic of many sugar derivatives. The presence of the imino group can influence its reactivity and biological activity, making it a subject of interest in research. Additionally, its molecular structure allows for various interactions with biological macromolecules, which may contribute to its pharmacological properties. As with many chemical substances, handling should be done with care, and safety data should be consulted to ensure proper precautions are taken during use.
Formula:C6H13NO4
InChI:InChI=1/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4+,5+,6?/m0/s1
Synonyms:- 2,5-Dideoxy-2,5-imino-D-glucitol
- (2R,4R,5S)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol
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Found 5 products.
2,5-Anhydro-2,5-imino-D-glucitol
CAS:Controlled Product<p>Applications Many pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and are believed to associate with acidic amino acids at the active site. Inhibition of glycohydrolases could be of therapeutic value for the treatment of viral infections, cancer, diabetes, and obesity.<br>References Fellows, L.E., et al.: J. Chem. Brit., 287, (1987), Elbein, A.D.: Annu. Rev. Biochem., 56, 497 (1987), Fleet, G.W., et al.: J. Chem. Brit., 287, (1989) Baxter, E.W., et al.: J. Org. Chem., 59, 3175 (1994); Tyms, A.S. et al. Lancet 1025, (1987); Spearman, M.A. et al. Expt. Cell Res. 168, 116 (1987); Horii, S. et al. J. Med. Chem. 29, 1038 (1986).<br></p>Formula:C6H13NO4Color and Shape:NeatMolecular weight:163.172,5-Dideoxy-2,5-imino-D-glucitol
CAS:<p>2,5-Dideoxy-2,5-imino-D-glucitol is a potent inhibitor of glycosidases. It has been shown to have significant antifungal activity against Candida albicans in the caco-2 cell model system. 2,5-Dideoxy-2,5-imino-D-glucitol inhibits β-(1→3)-glycosidase activity by binding to the active site of the enzyme and preventing substrate hydrolysis. The compound is also an enantiopure and asymmetric synthesis. This drug has been shown to be a model system for studying glycosidase inhibition.</p>Formula:C6H13NO4Purity:Min. 95%Molecular weight:163.17 g/mol
