CAS 132327-80-1

N(alpha)-fmoc-N(delta)-trityl-L-glutamine

Description:

N(alpha)-Fmoc-N(delta)-trityl-L-glutamine is a protected derivative of the amino acid L-glutamine, commonly used in peptide synthesis and research. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino terminus, allowing for selective reactions at the carboxyl end or within the peptide chain without interference from the amine. The "trityl" group, which is a bulky aromatic protecting group, is attached to the side chain amine of the glutamine residue, providing stability and preventing unwanted reactions during synthesis. This compound is typically white to off-white in appearance and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its stability under standard laboratory conditions makes it suitable for various synthetic applications. The use of such protected amino acids is crucial in the field of peptide chemistry, particularly in solid-phase peptide synthesis, where the sequential addition of amino acids is performed to construct peptides with specific sequences and functionalities.

Formula: C₃₉H₃₄N₂O₅

InChI: InChI=1/C39H34N2O5/c42-36(41-39(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29)25-24-35(37(43)44)40-38(45)46-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34/h1-23,34-35H,24-26H2,(H,40,45)(H,41,42)(H,43,44)/t35-/m1/s1

InChI key: InChIKey=WDGICUODAOGOMO-DHUJRADRSA-N

SMILES: C(NC(CC[C@H](NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(O)=O)=O)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-oxo-5-(tritylamino)pentanoic acid
• <span class="text-smallcaps">L</span>-Glutamine, N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
• D-Glutamine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
• Fmoc-<span class="text-smallcaps">L</span>-Gln(Trt)-OH
• Fmoc-Gln(Trt)-OH
• Fmoc-L-Gln(Trt)-OH
• Fmoc-L-Glutamine(Trityl)
• N-Fmoc-N'-trityl-L-glutamine
• N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-glutamine
• N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-<span class="text-smallcaps">L</span>-glutamine
• Nalpha-Fmoc-Ndelta-trityl-L-glutamine
• na-fmoc-N-delta-trityl-L-glutamine
• N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-glutamine
• L-Glutamine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
• N-ALPHA-FMOC-N-GAMMA-TRITYL-L-GLUTAMINE
• N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-OMEGA-TRITYL-L-GLUTAMINE
• FMOC-L-GLN(TRT)
• FMOC-GLUTAMINE(TRT)-OH
• N-ALPHA-FMOC-N-DELTA-TRITYL-L-GLUTAMINE
• N-ALPHA-FMOC-N-TRITYL-L-GLUTAMINE
• FMOC-GLN(TRT)
• FMOC-N-TRITYL-L-GLUTAMINE
• NA-FMOC-NG-TRITYL-L-GLUTAMINE
• FMOC-L-GLUTAMINE (TRT)
• NALPHA-(9-FLUORENYLMETHOXYCARBONYL)-NR-TRITYL-GLUTAMINE
• FMOC-N-GAMMA-TRITYL-L-GLUTAMINE
• N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-GAMMA-TRITYL-GLUTAMINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-GAMMA-TRITYL-L-GLUTAMINE
• FMOC-L-GLN(TRITYL)
• FMOC-N-DELTA-TRITYL-L-GLUTAMINE

Nα-Fmoc-Nδ-trityl-L-glutamine, 98%

CAS: 132327-80-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₉H₃₄N₂O₅

Purity: 98%

Molecular weight: 610.71

Ref: 02-H59080

Fmoc-Gln(Trt)-OH

CAS: 132327-80-1

M03356 - Fmoc-Gln(Trt)-OH

Formula: C₃₉H₃₄N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 610.71

Ref: 10-M03356

Fmoc-Gln(Trt)-OH

CAS: 132327-80-1

Bachem ID: 4014949.

Formula: C₃₉H₃₄N₂O₅

Purity: 99.66%

Color and Shape: White

Molecular weight: 610.71

Ref: 01-4014949

L-Glutamine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-

CAS: 132327-80-1

Formula: C₃₉H₃₄N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 610.6977

Ref: IN-DA0010K6

Fmoc-Gln(Trt)-OH

CAS: 132327-80-1

Formula: C₃₉H₃₄N₂O₅

Purity: ≥ 98.5%

Color and Shape: White to off-white powder

Molecular weight: 610.71

Ref: 7W-GM4670

FMOC-Gln(Trt)-OH

CAS: 132327-80-1

FMOC-Gln(Trt)-OH

Formula: C₃₉H₃₄N₂O₅

Purity: 98%

Color and Shape: white powder

Molecular weight: 610.70g/mol

Ref: 54-OR54572

Fmoc-Gln(Trt)-OH

CAS: 132327-80-1

Formula: C₃₉H₃₄N₂O₅

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 610.71

Ref: 3B-F1284

Fmoc-Gln(Trt)-OH

CAS: 132327-80-1

Fmoc-Gln(Trt)-OH is a synthetic amino acid that contains a hydroxyl group in its side chain. The hydroxyl group of Fmoc-Gln(Trt)-OH can react with other molecules and form conjugates, which leads to impurities in the final product. In the synthesis of Fmoc-Gln(Trt)-OH, the reaction time can affect the efficiency of the synthesis. In order to produce a high concentration of Fmoc-Gln(Trt)-OH, it is necessary to use chromatographic methods for purification. Fmoc-Gln(Trt)-OH has been shown to be beneficial as an anticancer agent due to its ability to inhibit serine proteases.

Formula: C₃₉H₃₄N₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 610.7 g/mol

Ref: 3D-FF15875

Fmoc-Gln(Trt)-OH

CAS: 132327-80-1

Fmoc-Gln(Trt)-OH is a synthetic, acid-stable, antimicrobial peptide that can be used as an analytical reagent. It has been shown to inhibit the growth of mammalian cells and bacterial cells in vitro by binding to nicotinic acetylcholine receptors. Fmoc-Gln(Trt)-OH contains sequences that are found in microbial proteins, suggesting that it may have antimicrobial activity against bacteria. The chemical diversity within this molecule may also contribute to its antimicrobial activity.

Formula: C₃₉H₃₄N₂O₅

Purity: Min. 98.0 Area-%

Molecular weight: 610.72 g/mol

Ref: 3D-FLQ-1755-PI

Na-FMOC-No-Trityl-L-Glutamine (FMOC-Gln(TRT)-OH) extrapure, 98%

CAS: 132327-80-1

Formula: C₃₉H₃₄N₂O₅

Purity: min. 98%

Color and Shape: White to off - white to pale yellow, Powder, Clear, Colourless to pale yellow

Molecular weight: 610.70

Ref: SR-21282