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CAS 132388-57-9

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Z-Asn(Trt)-OH

Description:
Z-Asn(Trt)-OH, also known as Z-asparagine (Trt) hydroxylamine, is a protected form of the amino acid asparagine. The "Z" denotes the benzyloxycarbonyl (Z) protecting group, which is commonly used in peptide synthesis to protect the amino group from unwanted reactions. The "Trt" refers to the trityl protecting group on the side chain, which protects the carboxamide functionality of asparagine. This compound is typically utilized in peptide synthesis and research involving amino acids, allowing for selective reactions while preventing side reactions that could occur at the amino or carboxamide groups. Z-Asn(Trt)-OH is generally stable under standard laboratory conditions but may require specific conditions for deprotection to yield the free amino acid. Its solubility is influenced by the presence of the protecting groups, and it is often used in organic synthesis and biochemistry for the construction of peptides and proteins. As with all chemical substances, proper handling and safety precautions should be observed when working with Z-Asn(Trt)-OH.
Formula:C31H28N2O5
InChI:InChI=1/C31H28N2O5/c34-28(21-27(29(35)36)32-30(37)38-22-23-13-5-1-6-14-23)33-31(24-15-7-2-8-16-24,25-17-9-3-10-18-25)26-19-11-4-12-20-26/h1-20,27H,21-22H2,(H,32,37)(H,33,34)(H,35,36)/t27-/m0/s1
SMILES:c1ccc(cc1)COC(=N[C@@H](CC(=NC(c1ccccc1)(c1ccccc1)c1ccccc1)O)C(=O)O)O
Synonyms:
  • N-Cbz-N'-trityl-L-asparagine
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