CAS 132388-59-1: N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparagine
Description:N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparagine, commonly referred to as Fmoc-Asn(Trt)-OH, is a protected derivative of the amino acid L-asparagine. This compound features a fluorenylmethoxycarbonyl (Fmoc) group, which is a widely used protective group in peptide synthesis, allowing for selective deprotection under mild conditions. The triphenylmethyl (Trt) group provides additional stability and protection for the amino group, making it suitable for solid-phase peptide synthesis. The structure of this compound includes a chiral center, contributing to its potential applications in the synthesis of biologically active peptides. It is typically used in research and pharmaceutical applications, particularly in the development of peptide-based drugs. The compound is characterized by its relatively high molecular weight and specific solubility properties, which can influence its behavior in various solvents. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance.
Formula:C38H32N2O5
InChI:InChI=1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1
InChI key:InChIKey=KJYAFJQCGPUXJY-UMSFTDKQSA-N
SMILES:O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC(C(=O)O)CC(=O)NC(C=4C=CC=CC4)(C=5C=CC=CC5)C=6C=CC=CC6
- Synonyms:
- (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid
- (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-3-[(triphenylmethyl)carbamoyl]propanoic acid
- (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(tritylamino)butanoate
- <span class="text-smallcaps">L</span>-Asparagine, N<sup>2</sup>-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
- Fmoc-<span class="text-smallcaps">L</span>-Asn(Trt)-OH
- Fmoc-Asn(Trt)-OH
- Fmoc-L-Asn(Trt)-OH
- N-Fmoc-N'-trityl-L-asparagine
- N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit
- N<sup>2</sup>-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-<span class="text-smallcaps">L</span>-asparagine
- See more synonyms
- Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine
- N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine
- na-fmoc-N-gamma-trityl-L-asparagine
- L-Asparagine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
- N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparagine