CAS 132388-59-1

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparagine

Description:

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-L-asparagine, commonly referred to as Fmoc-Asn(Trt)-OH, is a protected derivative of the amino acid L-asparagine. This compound features a fluorenylmethoxycarbonyl (Fmoc) group, which is a widely used protective group in peptide synthesis, allowing for selective deprotection under mild conditions. The triphenylmethyl (Trt) group provides additional stability and protection for the amino group, making it suitable for solid-phase peptide synthesis. The structure of this compound includes a chiral center, contributing to its potential applications in the synthesis of biologically active peptides. It is typically used in research and pharmaceutical applications, particularly in the development of peptide-based drugs. The compound is characterized by its relatively high molecular weight and specific solubility properties, which can influence its behavior in various solvents. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance.

Formula: C₃₈H₃₂N₂O₅

InChI: InChI=1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1

InChI key: InChIKey=KJYAFJQCGPUXJY-UMSFTDKQSA-N

SMILES: C(NC(C[C@H](NC(OCC1C=2C(C=3C1=CC=CC3)=CC=CC2)=O)C(O)=O)=O)(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid
• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-3-[(triphenylmethyl)carbamoyl]propanoic acid
• (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxo-4-(tritylamino)butanoate
• <span class="text-smallcaps">L</span>-Asparagine, N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-
• Fmoc-<span class="text-smallcaps">L</span>-Asn(Trt)-OH
• Fmoc-Asn(Trt)-OH
• Fmoc-L-Asn(Trt)-OH
• N-Fmoc-N'-trityl-L-asparagine
• N-alpha-(9-fluorenylmethoxycarbonyl)-N-gamma-trit
• N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-<span class="text-smallcaps">L</span>-asparagine
• Na-(9-Fluorenyl Methoxy Carbonyl)-Ng-Trityl-L-Asparagine
• N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine
• na-fmoc-N-gamma-trityl-L-asparagine
• L-Asparagine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nγ-trityl-L-asparagine

CAS: 132388-59-1

Formula: C₃₈H₃₂N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 596.68

Ref: 3B-F0508

Nα-Fmoc-Nγ-trityl-L-asparagine, 97%

CAS: 132388-59-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₈H₃₁N₂O₅

Purity: 97%

Molecular weight: 595.68

Ref: 02-H59536

Fmoc-Asn(Trt)-OH

CAS: 132388-59-1

Bachem ID: 4014948.

Formula: C₃₈H₃₂N₂O₅

Purity: 99.6%

Color and Shape: White

Molecular weight: 596.68

Ref: 01-4014948

L-Asparagine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-

CAS: 132388-59-1

Formula: C₃₈H₃₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 596.6711

Ref: IN-DA0010MP

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid

CAS: 132388-59-1

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid

Purity: 98%

Molecular weight: 596.68g/mol

Ref: 54-OR74376

Fmoc-Asn(Trt)-OH

CAS: 132388-59-1

Formula: C₃₈H₃₂N₂O₅

Purity: ≥ 99.0%

Color and Shape: White to almost white powder

Molecular weight: 596.67

Ref: 7W-GM6525

Fmoc-Asn(Trt)-OH

CAS: 132388-59-1

Fmoc-Asn(Trt)-OH is a pegylated molecule synthesized by attaching a polyethylene glycol (PEG) to the terminal amino acids. It has been shown that Fmoc-Asn(Trt)-OH inhibits peptide synthesis by inhibiting the formation of an enzyme-substrate complex. This inhibition prevents the transfer of an amino acid from one protein chain to another, preventing the formation of a new chain and subsequent polymerization. Fmoc-Asn(Trt)-OH also has an inhibitory effect on polypeptide synthesis. The molecular weight of this compound is about 535 Daltons.

Formula: C₃₈H₃₂N₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 596.67 g/mol

Ref: 3D-FF15879

Fmoc-Asn(Trt)-OH

CAS: 132388-59-1

Fmoc-L-Asn(Trt)-OH is an Fmoc-protected amino acid with a free amine group. It is used as a building block for peptide synthesis and can be used in the production of polymeric materials for drug delivery. The Fmoc-protected amino acids are stable, but can be deprotected by treatment with trifluoroacetic acid or other strong acid. They are also soluble in organic solvents, such as dimethylformamide and DMF, which makes them useful for peptide synthesis. This product has minimal activity.BR>
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Formula: C₃₈H₃₂N₂O₅

Purity: Min. 98.0 Area-%

Molecular weight: 596.69 g/mol

Ref: 3D-FLN-1754-PI

Fmoc-Asn(Trt)-OH

CAS: 132388-59-1

M03352 - Fmoc-Asn(Trt)-OH

Formula: C₃₈H₃₂N₂O₅

Purity: 98%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 596.683

Ref: 10-M03352

Fmoc-Asn(Trt)-OH

CAS: 132388-59-1

Formula: C₃₈H₃₂N₂O₅

Molecular weight: 596.7

Ref: ST-EA-CP-L28032

FMOC-N-Trityl-L-Asparagine (FMOC-Asn(Trt)-OH) extrapure, 99%

CAS: 132388-59-1

Formula: C₃₈H₃₂N₂O₅

Purity: min. 99%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 596.67

Ref: SR-49323