CAS 132541-62-9

15,15'-epoxy-beta,beta-carotene

Description:

15,15'-Epoxy-beta,beta-carotene, with the CAS number 132541-62-9, is a carotenoid derivative characterized by its unique epoxy functional group at the 15,15' positions of the beta-carotene structure. This compound is a product of the oxidation of beta-carotene, which is a well-known pigment found in various plants and is responsible for the orange color in carrots and other vegetables. The presence of the epoxy group alters its chemical reactivity and stability compared to its parent compound. 15,15'-Epoxy-beta,beta-carotene exhibits antioxidant properties, which can contribute to its potential health benefits, including its role in protecting cells from oxidative stress. Additionally, it may have implications in the field of nutrition and food science, particularly in the study of carotenoid metabolism and bioavailability. Its solubility characteristics are similar to other carotenoids, being more soluble in organic solvents than in water. Overall, this compound is of interest in both biochemical research and potential applications in health and nutrition.

Formula: C₄₀H₅₆O

InChI: InChI=1/C40H56O/c1-29(21-23-35-33(5)19-13-25-39(35,7)8)15-11-17-31(3)27-37-38(41-37)28-32(4)18-12-16-30(2)22-24-36-34(6)20-14-26-40(36,9)10/h11-12,15-18,21-24,27-28,37-38H,13-14,19-20,25-26H2,1-10H3/b17-11+,18-12+,23-21+,24-22+,29-15+,30-16+,31-27+,32-28+

Synonyms:

• 15,15'-epoxy-beta,beta-carotene
• beta-carotene 15,15'-epoxide
• beta,beta-Carotene, 15,15'-epoxy-15,15'-dihydro-
• 15,15'-dihydro-15,15'-epoxy-beta,beta-carotene
• 15-Ebbct
• 15,15'-Epoxy-15,15'-dihydro-beta,beta-carotene

β-Carotene-15,15'-epoxide

CAS: 132541-62-9

β-Carotene-15,15ʹ-epoxide acts as an XIAP antagonist with pro-apoptotic (Apoptosis) and anti-tumor properties, found in the leaves of Spondias mombin. In rat models of DMBA-induced breast cancer, it induces tumor cell apoptosis by binding to the BIR3 domain of the XIAP protein, thereby inhibiting its interaction with caspase-9. Additionally, β-carotene-15,15ʹ-epoxide significantly reduces BCL-2, COX-2, and TNF-α expression in tumor tissue, decreases MDA levels, enhances catalase activity, and modulates biochemical markers in serum such as LDH, ALP, and ALT, indicating its antioxidant, anti-inflammatory, and metabolic protective effects. This compound is useful for researching inflammation-related diseases and tumors such as breast cancer.

Formula: C₄₀H₅₆O

Color and Shape: Solid

Molecular weight: 552.872

Ref: TM-TN10594