CAS 13256-32-1

N,N'-dimethylnitrosourea

Description:

N,N'-Dimethylnitrosourea (DMNU) is a potent alkylating agent and a member of the nitrosourea family, characterized by its ability to introduce alkyl groups into DNA, leading to mutagenic and carcinogenic effects. It is a colorless to pale yellow liquid that is soluble in organic solvents but has limited solubility in water. DMNU is known for its high reactivity, particularly with nucleophilic sites in biological molecules, which makes it a valuable compound in cancer research and as a tool in molecular biology for inducing mutations in experimental models. Due to its toxic and carcinogenic properties, DMNU must be handled with extreme caution in laboratory settings, following strict safety protocols to minimize exposure. Its use is primarily restricted to research applications, and it is not approved for therapeutic use in humans. The compound's structure features a nitrosourea moiety, which is responsible for its reactivity and biological effects, making it a significant compound in the study of cancer mechanisms and drug development.

Formula: C₃H₇N₃O₂

InChI: InChI=1/C3H7N3O2/c1-4-3(7)6(2)5-8/h1-2H3,(H,4,7)

InChI key: InChIKey=BHMHNSQLZKUIMD-UHFFFAOYSA-N

SMILES: C(N(N=O)C)(NC)=O

Synonyms:

• 1,3-Dimethyl-1-Nitrosourea
• 1,3-Dimethyl-1-nitrourea
• 1,3-Dimethyl-N-Nitrosourea
• 1,3-Dimethylnitrosourea
• 1-Nitroso-1,3-dimethylurea
• Dimethylnitrosourea
• Dimethylnur
• Dimethynur
• N,N′-Dimethyl-N-nitrosourea
• N-Methyl-N′-methyl-N-nitrosourea
• N-Nitroso-N,N′-dimethylurea
• NSC 48893
• Nitrosodimethylurea
• Urea, 1,3-dimethyl-1-nitroso-
• Urea, N,N′-dimethyl-N-nitroso-

1,3-Dimethyl-3-nitrosourea

CAS: 13256-32-1

Formula: C₃H₇N₃O₂

Color and Shape: Solid

Molecular weight: 117.1066

Ref: IN-DA0010U7

N-Nitroso N,N'-Dimethylurea

CAS: 13256-32-1

Formula: C₃H₇N₃O₂

Molecular weight: 117.11

Ref: 4Z-U-0636

1,3-Dimethyl-3-nitrosourea (Contains 25-35% water)

Controlled Product

CAS: 13256-32-1

Stability Temperature Sensitive
Applications 1,3-Dimethyl-3-nitrosourea is a carcinogen.
References Luan, F., et al.: Chem. Res. Toxicol., 18, 198 (2005); Hasegawa, R., et al.: Cancer Lett., 123, 185 (1998)

Formula: C₃H₇N₃O₂

Color and Shape: Neat

Molecular weight: 117.11

Ref: TR-D471443