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CAS 13258-72-5

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Cephalosporin P1

Description:
Cephalosporin P1 is a member of the cephalosporin class of antibiotics, which are characterized by their beta-lactam structure that is crucial for their antibacterial activity. This compound is derived from the fungus Acremonium, which produces various cephalosporins. Cephalosporin P1 exhibits a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, making it effective in treating various bacterial infections. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection due to its instability in acidic environments, which limits oral bioavailability. Cephalosporin P1 may also possess certain pharmacokinetic properties, such as distribution and elimination half-life, that influence its therapeutic use. Additionally, like other beta-lactam antibiotics, it may be subject to resistance mechanisms, including the production of beta-lactamases by certain bacteria. Overall, Cephalosporin P1 represents an important tool in the arsenal against bacterial infections, particularly in cases where other antibiotics may be ineffective.
Formula:C33H50O8
InChI:InChI=1S/C33H50O8/c1-17(2)10-9-11-21(30(38)39)26-22-12-13-25-31(6)15-14-23(36)18(3)27(31)28(41-20(5)35)29(37)33(25,8)32(22,7)16-24(26)40-19(4)34/h10,18,22-25,27-29,36-37H,9,11-16H2,1-8H3,(H,38,39)/b26-21-/t18-,22+,23-,24+,25+,27-,28-,29+,31-,32+,33-/m1/s1
InChI key:InChIKey=YJJWILCYIMMPAS-VALXSNPUSA-N
SMILES:C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(CC[C@]1([C@]4(C)[C@@]([C@@H](OC(C)=O)[C@@H]2O)([C@H](C)[C@H](O)CC4)[H])[H])[H]
Synonyms:
  • 29-Nordammara-17(20),24-dien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dihydroxy-, (3α,4α,6α,7β,8α,9β,13α,14β,16β,17Z)-
  • Cephalosporin P1
  • (3α,4α,6α,7β,8α,9β,13α,14β,16β,17Z)-6,16-Bis(acetyloxy)-3,7-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid
  • Acremonic acid
  • 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,6α,7β,16β-tetrahydroxy-, 6,16-diacetate, (Z)-
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