CAS 132619-66-0

2',3'-dideoxycytidine 5'-triphosphate*sodium

Description:

2',3'-Dideoxycytidine 5'-triphosphate sodium (ddCTP) is a nucleotide analog that plays a significant role in molecular biology, particularly in DNA synthesis and sequencing. It is a derivative of cytidine, where the hydroxyl groups at the 2' and 3' positions of the ribose sugar are replaced with hydrogen atoms, rendering it a dideoxynucleotide. This modification prevents the formation of phosphodiester bonds during DNA chain elongation, making ddCTP a crucial tool in studies involving DNA polymerases and in the development of antiviral therapies. The sodium salt form enhances its solubility in aqueous solutions, facilitating its use in various biochemical applications. ddCTP is often utilized in techniques such as PCR and Sanger sequencing, where its incorporation leads to chain termination, allowing for the determination of nucleotide sequences. Its chemical structure includes a triphosphate group, which is essential for its function as a substrate in enzymatic reactions. Overall, ddCTP is a valuable compound in both research and therapeutic contexts, particularly in the study of nucleic acids.

Formula: C₉H₁₇N₃NaO₁₂P₃

InChI: InChI=1/C9H16N3O12P3.Na/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16;/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16);/q;+1/p-1/t6-,8+;/m0./s1

SMILES: C1CC(n2ccc(=N)nc2O)OC1COP(=O)(O)OP(=O)(O)OP(=O)(O)O.[Na]

Synonyms:

• triphosphoric acid, [(2S,5R)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)tetrahydro-2-furanyl]methyl ester, monosodium salt
• ddCTP trisodium salt solution
• 2',3'-Dideoxycytidine 5'-triphosphoric acid
• 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE SODIUM SALT
• 2',3'-Dideoxycytidine 5'-triphosphate sodium salt >=90% (HPLC)
• 2',3'-Dideoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution
• 1-[4-Amino-2-oxopyrimidine-1(2H)-yl]-1,2,3-trideoxy-β-D-glycero-pentofuranose 5-triphosphoric acid
• 2',3'-Deoxycytidine-5'-triphosphate, sodium salt solution
• 2'3'-Dideoxycytidine 5'-triphosphate sodiuM salt (ddCTP)
• 2’,3’-dideoxycytidine5’-triphosphate*sodium
• 2',3'-DIDEOXYCYTIDINE-5'-O-TRIPHOSPHATE SODIUM SALT
• DDCTP
• DDCTP SODIUM SALT
• ddCTP (disodium)
• 2μ,3μ-Dideoxycytidine 5μ-triphosphate solution sodium salt

2',3'-Dideoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution

CAS: 132619-66-0

2',3'-Dideoxycytidine-5'-triphosphate lithium salt is a novel nucleoside, which can be used in the synthesis of oligonucleotides and DNA. The phosphoramidite is highly reactive and stable, and has been shown to have antiviral activity against influenza A virus. This chemical has also been shown to inhibit the growth of cancer cells by inhibiting DNA synthesis.

Formula: C₉H₁₆N₃O₁₂P₃

Purity: Min. 95%

Molecular weight: 451.16 g/mol

Ref: 3D-ND32066