CAS 132628-16-1

N-(2-Phenylacetyl)guanosine

Description:

N-(2-Phenylacetyl)guanosine is a modified nucleoside that features a guanosine base linked to a phenylacetyl group. This compound is characterized by its unique structural properties, which include a purine base (guanine) attached to a ribose sugar, along with the phenylacetyl moiety that enhances its chemical reactivity and potential biological activity. The presence of the phenylacetyl group can influence the compound's solubility, stability, and interaction with biological targets, making it of interest in medicinal chemistry and biochemistry. N-(2-Phenylacetyl)guanosine may exhibit various pharmacological properties, potentially acting as an inhibitor or modulator in biochemical pathways. Its CAS number, 132628-16-1, allows for easy identification and reference in scientific literature and databases. As a nucleoside analog, it may also be studied for its role in nucleic acid research and therapeutic applications, particularly in the context of antiviral or anticancer strategies. Overall, this compound represents a significant area of interest for researchers exploring nucleoside modifications and their implications in drug design.

Formula: C₁₈H₁₉N₅O₆

InChI: InChI=1S/C18H19N5O6/c24-7-10-13(26)14(27)17(29-10)23-8-19-12-15(23)21-18(22-16(12)28)20-11(25)6-9-4-2-1-3-5-9/h1-5,8,10,13-14,17,24,26-27H,6-7H2,(H2,20,21,22,25,28)/t10-,13-,14-,17-/m1/s1

InChI key: InChIKey=IRSCBAKCFOLZNC-IWCJZZDYSA-N

SMILES: O=C1C2=C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)NC(NC(CC4=CC=CC=C4)=O)=N1

Synonyms:

• Guanosine, N-(2-phenylacetyl)-
• Guanosine, N-(phenylacetyl)-
• N-(2-Phenylacetyl)guanosine
• N-(phenylacetyl)guanosine
• N2-Phenylacetyl Ribonucleoside Guanosine

GUANOSINE, N-(2-PHENYLACETYL)-

CAS: 132628-16-1

Formula: C₁₈H₁₉N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 401.3734

Ref: IN-DA0010WN

N2-Phenylacetyl Guanosine

CAS: 132628-16-1

N2-Phenylacetyl Guanosine

Purity: 98%

Molecular weight: 401.37g/mol

Ref: 54-OR1014211

N2-Phenylacetylguanosine

CAS: 132628-16-1

Ref: 7W-GN7393

N2-Phenylacetylguanosine

CAS: 132628-16-1

N2-Phenylacetylguanosine is a novel, modified ribonucleoside with anticancer and antiviral activities. It can be used as a monophosphate or diphosphate. N2-Phenylacetylguanosine is synthesized from 2-phenylethylamine and guanosine using phosphoramidite chemistry. It has been shown to activate DNA synthesis and cell proliferation in vitro, which may lead to tumor growth inhibition.

Formula: C₁₈H₁₉N₅O₆

Purity: Min. 99 Area-%

Color and Shape: Powder

Molecular weight: 401.37 g/mol

Ref: 3D-NP06294

N2-Phenylacetylguanosine

CAS: 132628-16-1

N2-Phenylacetylguanosine is a compound that has shown potential in the treatment of erectile dysfunction and emissions. It is commonly used as an advanced intermediate in the synthesis of various pharmaceuticals, including monoclonal antibodies like imatinib. N2-Phenylacetylguanosine has also been studied for its role in fatty acid metabolism and its ability to inhibit the plpro enzyme. Additionally, it has shown promise as a neutralizing agent against certain strains of coronaviruses in human trials. This compound is not only relevant to the medical field but also finds applications in agriculture as it can be used as an ingredient in herbicides. N2-Phenylacetylguanosine shares similarities with sildenafil, a well-known medication for erectile dysfunction, making it an interesting subject for further research and development.

Formula: C₁₈H₁₉N₅O₆

Purity: Min. 99 Area-%

Molecular weight: 401.37 g/mol

Ref: 3D-W-201082

N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide

CAS: 132628-16-1

Formula: C₁₈H₁₉N₅O₆

Purity: 98%

Molecular weight: 401.379

Ref: 10-F546214