CAS 132685-02-0

1,1′-Ethylidenebis[L-tryptophan]

Description:

1,1′-Ethylidenebis[L-tryptophan], with the CAS number 132685-02-0, is a synthetic compound derived from the amino acid tryptophan, which is known for its role in protein synthesis and as a precursor to serotonin. This compound features a unique structure where two L-tryptophan units are linked by an ethylidene bridge, enhancing its stability and potentially altering its biological activity compared to free tryptophan. It is characterized by its aromatic indole side chains, which contribute to its ability to participate in various biochemical interactions. The compound may exhibit properties such as solubility in polar solvents, and its behavior in biological systems could be influenced by the presence of the ethylidene linkage. As a derivative of tryptophan, it may also have implications in neurochemistry and pharmacology, particularly in studies related to mood regulation and sleep. However, specific applications and biological effects would require further investigation to fully understand its potential uses and mechanisms of action.

Formula: C₂₄H₂₆N₄O₄

InChI: InChI=1/C24H26N4O4/c1-14(27-12-15(10-19(25)23(29)30)17-6-2-4-8-21(17)27)28-13-16(11-20(26)24(31)32)18-7-3-5-9-22(18)28/h2-9,12-14,19-20H,10-11,25-26H2,1H3,(H,29,30)(H,31,32)/t19-,20-/m0/s1

InChI key: InChIKey=DETVQFQGSVEQBH-PMACEKPBSA-N

SMILES: C(C)(N1C=2C(C(C[C@@H](C(O)=O)N)=C1)=CC=CC2)N3C=4C(C(C[C@@H](C(O)=O)N)=C3)=CC=CC4

Synonyms:

• (2S,2'S)-3,3'-[ethane-1,1-diylbis(1H-indole-1,3-diyl)]bis(2-aminopropanoic acid) (non-preferred name)
• 1,1'-Ethylidene-Bis(L-Tryptophan)
• 1,1'-Ethylidene-Bis(L-Trytophan)
• 1,1′-Ethylidenebis[<span class="text-smallcaps">L</span>-tryptophan]
• <span class="text-smallcaps">L</span>-Tryptophan, 1,1′-ethylidenebis-
• Contaminant 97
• EBT
• 1,1′-Ethylidenebis[L-tryptophan]
• L-Tryptophan, 1,1′-ethylidenebis-
• Tryptophan Related CoMpound A
• Tryptophan Related Compound A (1,1''-ethylidene-bis(L-tryptophan)) (1700512)
• PEAK E
• Tryptophan Related Compound A(Secondary Standards traceble to USP)
• Tadalafil Impurity (1,1?'-thylidenebistryptophan)
• 1,1'-Ethylidenebistryptophan CRS
• Tadalafil Impurity Q
• (2S,2'S)-3,3'-(1,1'-(Ethane-1,1-diyl)bis(1H-indole-3,1-diyl))bis(2-aminopropanoic acid)
• Tryptophan USP Related Compound A
• 1,1'-ethylidenebis
• 3,3'-[Ethylidenebis(1H-indole-1,3-d
• Tryptophan Related Compound A (15 mg) (1,1'-ethylidene-bis-(L-tryptophan))

1,1'-ETHYLIDENEBISTRYPTOPHAN CRS

CAS: 132685-02-0

1,1'-ETHYLIDENEBISTRYPTOPHAN CRS

Formula: C₂₄H₂₆N₄O₄

Color and Shape: Powder

Molecular weight: 434.4876

Ref: 41-E2205500

Tryptophan Related Compound A ((2S,2'S)-3,3'-[Ethane-1,1-diylbis(1H-indole-1,3-diyl)]bis(2-aminopropanoic acid))

CAS: 132685-02-0

Aromatic or modified aromatic drugs with nitrogen heter

Formula: C₂₄H₂₆N₄O₄

Color and Shape: Off-White Solid

Molecular weight: 434.19541

Ref: 45-1700512

1,1'-Ethylidene-bis-(L-tryptophan)

CAS: 132685-02-0

Formula: C₂₄H₂₆N₄O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 434.4876

Ref: IN-DA009C17

1,1′-Ethylidenebis[L-tryptophan]

CAS: 132685-02-0

1,1′-Ethylidenebis[L-tryptophan]

Purity: 98%

Ref: 54-OR1036708

Tryptophan EP Impurity A DiHCl (Tryptophan USP Related Compound A DiHCl)

CAS: 132685-02-0

Formula: C₂₄H₂₆N₄O₄·2HCl

Molecular weight: 434.50 2*36.46

Ref: 4Z-T-2075

Tryptophan EP Impurity A HCl (Tryptophan USP Related Compound A HCl)

CAS: 132685-02-0

Formula: C₂₄H₂₆N₄O₄·HCl

Molecular weight: 434.50 36.46

Ref: 4Z-T-2076

Tryptophan EP Impurity A

Controlled Product

CAS: 132685-02-0

Formula: C₂₄H₂₆N₄O₄

Color and Shape: Neat

Molecular weight: 434.49

Ref: 86-MM0172.09

1,1'-Ethylidenebis[L-tryptophan]

Controlled Product

CAS: 132685-02-0

Stability Decomposes under acidic condition, Hygroscopic
Applications 1,1’-Ethylidenebis[L-tryptophan] is a L-tryptophan (T947210) contaminant found in the peripheral blood mononuclear cells from patients with functional somatic syndromes.
References Barth, H., et al.: Clin. Experiment. Inmmunol., 126, 187 (2001); Simat, T.J., et al.: Adv. Experi. Med. Biol., 467, 469 (1999);

Formula: C₂₄H₂₆N₄O₄

Color and Shape: White To Light Yellow Brown

Molecular weight: 434.49

Ref: TR-E919880

1,1'-Ethylidene-bis-(L-tryptophan)

CAS: 132685-02-0

L-tryptophan is an essential amino acid that is used in the synthesis of proteins. It is also a precursor to serotonin, an important neurotransmitter. L-tryptophan is found in many foods, including milk, eggs, fish, meat and some beans. It can be taken as a dietary supplement or as a drug for the treatment of depression. The chemical structure of L-tryptophan consists of 1,1'-ethylidene-bis-(L-tryptophan). This molecule has been shown to be synthesized from subcutaneous tissues and can be detected by immunohistochemical staining methods. L-Tryptophan has been shown to inhibit protein synthesis in muscle tissue and subcutaneous tissue.

Formula: C₂₄H₂₆N₄O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 434.49 g/mol

Ref: 3D-FE16364

Tryptophan EP Impurity A

CAS: 132685-02-0

Formula: C₂₄H₂₆N₄O₄

Molecular weight: 434.5

Ref: ST-EA-CP-T90001

1,1'-Ethylidene-bis-(L-tryptophan)

CAS: 132685-02-0

1,1'-Ethylidene-bis-(L-tryptophan) is a potential impurity in L-tryptophan commercial products, promoting EoL-3 eosinophilic leukemia cell proliferation, enhancing eosinophil cationic protein release from human peripheral blood eosinophils, and boosting IL-5 production in human T cells. At 40 µg/kg, it triggers fascia thickening, mast cell infiltration, inflammation, and fibrosis in mouse superficial adipose and panniculus carnosus tissues, serving as an eosinophilia-myalgia syndrome research model.

Formula: C₂₄H₂₆N₄O₄

Color and Shape: Solid

Molecular weight: 434.49

Ref: TM-T84937