CAS 13269-35-7
:(R)-Atropine
Description:
(R)-Atropine is a tropane alkaloid derived from the Atropa belladonna plant, commonly known as deadly nightshade. It is characterized by its chiral nature, existing as two enantiomers, with (R)-atropine being the more biologically active form. This compound is a competitive antagonist of the muscarinic acetylcholine receptors, which plays a significant role in its pharmacological effects, including its ability to inhibit parasympathetic nervous system activity. As a result, (R)-atropine is utilized in various medical applications, such as treating bradycardia, reducing salivation during surgery, and as an antidote for organophosphate poisoning. The substance is typically encountered as a white to off-white crystalline powder, with a relatively low solubility in water but higher solubility in organic solvents. Its molecular structure includes a tropane ring, which is essential for its biological activity. Due to its potent effects, (R)-atropine must be used with caution, as it can lead to side effects such as dry mouth, blurred vision, and increased heart rate.
Formula:C17H23NO3
InChI:InChI=1/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13?,14?,15?,16-/m0/s1
InChI key:InChIKey=RKUNBYITZUJHSG-JJXSEGSLSA-N
SMILES:O(C([C@@H](CO)C1=CC=CC=C1)=O)[C@@H]2C[C@]3(N(C)[C@@](C2)(CC3)[H])[H]
Synonyms:- (+)-Atropine
- (+)-Hyoscyamine
- (R)-Atropine
- 8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2R)-3-hydroxy-2-phenylpropanoate
- <span class="text-smallcaps">D</span>-Hyoscyamine
- Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αR)-
- Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(R)-endo]-
- d-Atropine
- d-Hyoscyamine
- R-(+)-Hyoscyamine
- [(1α,5α)-8-Methyl-8-azabicyclo[3.2.1]octan-3β-yl]=(R)-α-(hydroxymethyl)phenylacetate
- Atropine Impurity 27
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.
D-Hyoscyamine
CAS:D-Hyoscyamine is a potent anticancer agent that has been shown to induce apoptosis in cancer cells. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cell growth and division. D-Hyoscyamine has been tested on both human and Chinese hamster ovary cells, and has demonstrated significant anticancer activity. It is an analog of several kinase inhibitors, including cyclin-dependent kinase (CDK) inhibitors, which are commonly used in cancer therapy. In addition to its anticancer properties, D-Hyoscyamine has also been found to have potential therapeutic applications for other diseases such as Alzheimer's disease and Parkinson's disease. It is derived from urine and acts as a potent inhibitor of protein kinases.Formula:C17H23NO3Purity:Min. 95%Molecular weight:289.4 g/mol
