
CAS 132699-72-0
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Found 1 products.
Big Endothelin-2 (Human, 1-37)
CAS:<p>Amino acids 1-37 of the Human Big Endothelian-2 peptide formed as a result of furin cleavage of proendothelin which in turn is produced from EDN2 gene transcription. Due to the actions of the Endothelin-Converting Enzymes: ECE-1 and ECE-2, Big Endothelin-2 is converted into Endothelin-2 (ET-2) peptide. ET-2 has affinity for ETA and ETB G-protein coupled receptors which are found in a variety of tissues, including lungs, heart, kidneys, uterus and vasculature. It is believed that ET-2 is a potent vasoconstrictor and may play a role in cancer, immunology and heart failure. This product has is available as a 0.1mg vial and has disulfide bonds between Cys1-Cys15 and Cys3-Cys11.</p>Formula:C188H269N45O56S4Purity:Min. 95%Molecular weight:4,183.7 g/mol
