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CAS 132699-73-1

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(leu31,pro34)-neuropeptide Y human

Description:
Neuropeptide Y (NPY) is a 36-amino acid peptide that plays a crucial role in various physiological processes, including appetite regulation, circadian rhythms, and stress response. The specific variant known as (Leu31,Pro34)-neuropeptide Y is a modified form of NPY, where leucine and proline are substituted at positions 31 and 34, respectively. This modification can influence the peptide's biological activity and receptor binding affinity. NPY primarily acts through Y receptors, which are G-protein coupled receptors, and its signaling is involved in neuroendocrine functions and modulation of neurotransmitter release. The CAS number 132699-73-1 identifies this specific peptide variant, which is often studied for its potential therapeutic applications in conditions such as obesity, anxiety, and other metabolic disorders. Characteristically, neuropeptide Y is known for its stability in biological systems and its ability to cross the blood-brain barrier, making it a significant focus in neuropharmacology and metabolic research.
Formula:C189H284N54O56S
Synonyms:
  • (Leu31,Pro34)-Neuropeptide Y (human, rat)
  • H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
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