CAS 132746-60-2

(2S,3S)-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine

Description:

The chemical substance known as (2S,3S)-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine, with the CAS number 132746-60-2, is a bicyclic compound featuring a nitrogen atom within its structure, indicative of its classification as an amine. This compound exhibits chirality, as denoted by the (2S,3S) configuration, which suggests that it has two stereocenters contributing to its three-dimensional arrangement. The presence of diphenylmethyl and methoxyphenyl groups indicates that it may possess significant lipophilicity, potentially influencing its pharmacokinetic properties. Such structural features often correlate with biological activity, making it of interest in medicinal chemistry. The bicyclic framework, specifically the azabicyclo[2.2.2]octane core, is known for its ability to mimic certain neurotransmitters, which may suggest potential applications in neuropharmacology. Overall, this compound's unique structural characteristics may contribute to its functional properties, warranting further investigation in the context of drug development and therapeutic applications.

Formula: C₂₈H₃₂N₂O

InChI: InChI=1/C28H32N2O/c1-31-25-15-9-8-14-24(25)20-29-27-23-16-18-30(19-17-23)28(27)26(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-15,23,26-29H,16-20H2,1H3/t27-,28-/m0/s1

InChI key: InChIKey=FLNYLINBEZROPL-NSOVKSMOSA-N

SMILES: [C@H]([C@H]1[C@@H](NCC2=C(OC)C=CC=C2)C3CCN1CC3)(C4=CC=CC=C4)C5=CC=CC=C5

Synonyms:

• (2S,3S)-2-(Diphenylmethyl)-N-(2-methoxybenzyl)quinuclidin-3-amine
• (2S,3S)-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
• (2S,3S)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
• 1-Azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-, (2S,3S)-
• 1-Azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-, (2S-cis)-
• Cp 96345
• (2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine
• 1-azabicyclo[2.2.2]octan-3-aMine
• (2S)-N-(2-Methoxybenzyl)-2β-benzhydryl-1-azabicyclo[2.2.2]octane-3β-amine
• (2S-cis)-2-(DiphenylMethyl)-N-[(2-Methoxyphenyl)Methyl]-
• (2S)-2β-(Diphenylmethyl)-N-(2-methoxybenzyl)-1-azabicyclo[2.2.2]octan-3β-amine
• CP-96345-1
• (2S)-2β-Diphenylmethyl-3β-(2-methoxybenzylamino)-1-azabicyclo[2.2.2]octane

CP-96,345

CAS: 132746-60-2

Formula: C₂₈H₃₂N₂O

Color and Shape: Solid

Molecular weight: 412.5665

Ref: IN-DA00113I

CP-96345

CAS: 132746-60-2

Formula: C₂₈H₃₂N₂O

Molecular weight: 412.57

Ref: 7W-GK6288

CP 96345

CAS: 132746-60-2

Formula: C₂₈H₃₂N₂O

Molecular weight: 412.58

Ref: 4Z-E-206002

CP 96345

Controlled Product

CAS: 132746-60-2

Formula: C₂₈H₃₂N₂O

Color and Shape: Neat

Molecular weight: 412.567

Ref: TR-C781210

CP-96345

CAS: 132746-60-2

CP-96345 is a peptide hormone that inhibits the release of inflammatory substances, such as substance P and prostaglandin E2. It has been shown to be effective in the treatment of bowel disease, including Crohn's disease and ulcerative colitis, as well as infectious diseases. CP-96345 inhibits neurokinin-1 receptor activation by binding to it and blocking its access to substances. This inhibition leads to an inhibition of the release of substance P, which is an important mediator for pain, inflammation, and disease activity. CP-96345 has also been shown to have cardioprotective effects in animal models by reducing oxidative injury caused by ischemia/reperfusion injury.

Formula: C₂₈H₃₂N₂O

Purity: Min. 95%

Molecular weight: 412.57 g/mol

Ref: 3D-HFA74660

CP 96345

CAS: 132746-60-2

CP 96345 is a NK1 receptor antagonist.

Formula: C₂₈H₃₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 412.57

Ref: TM-T22690