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CAS 132752-65-9

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Scopoletin b-D-Glucuronide

Description:
Scopoletin b-D-Glucuronide is a glycosylated derivative of scopoletin, a naturally occurring coumarin compound. This substance is characterized by the presence of a glucuronic acid moiety attached to the hydroxyl group of scopoletin, which enhances its solubility and bioavailability. It typically appears as a white to off-white powder and is soluble in water and various organic solvents. Scopoletin b-D-Glucuronide exhibits various biological activities, including antioxidant, anti-inflammatory, and potential anticancer properties, making it of interest in pharmacological research. Its role in metabolic processes is significant, as glucuronidation is a common phase II metabolic reaction that facilitates the excretion of xenobiotics and endogenous compounds. The compound is often studied in the context of herbal medicine and natural product chemistry, particularly in relation to plants known for their medicinal properties. As with many glucuronides, its stability and reactivity can be influenced by pH and the presence of enzymes such as glucuronidases.
Formula:C16H16O10
InChI:InChI=1/C16H16O10/c1-23-8-4-6-2-3-10(17)24-7(6)5-9(8)25-16-13(20)11(18)12(19)14(26-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13-,14?,16+/m0/s1
Synonyms:
  • 6-Methoxy-2-oxo-2H-1-benzopyran-7-yl b-D-Glucopyranosiduronic Acid
  • 6-Methoxy-2-oxo-2H-1-benzopyran-7-yl -D-Glucopyranosiduronic Acid
  • Scopoletin -D-Glucuronide
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Found 4 products.
  • (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((6-methoxy-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-ca…
    Indagoo
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    (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((6-methoxy-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

    CAS:
    Formula:C16H16O10
    Color and Shape:Solid
    Molecular weight:368.2922

    Ref: IN-DA00114F

    ne
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  • Scopoletin b-D-glucuronide
    Glentham
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    Scopoletin b-D-glucuronide

    CAS:

    Ref: 7W-GC4581

    ne
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  • Scopoletin β-D-Glucuronide
    TRC
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    Scopoletin β-D-Glucuronide

    Controlled Product
    CAS:
    <p>Applications A metabolite of Scopoletin.<br>References Ikushiro, S., et al.: Biochemistry, 36, 7154 (1997), Ghosh, S.S., et al.: J. Biol. Chem., 276, 42108 (2001), Gagne, J.F., et al.: Mol. Pharmacol., 62, 608 (2002), Jinno, H., et al.: Drug Metab. Dispos., 31, 108 (2003),<br></p>
    Formula:C16H16O10
    Color and Shape:Neat
    Molecular weight:368.29

    Ref: TR-S200510

    1mg
    298.00€
  • Scopoletin b-D-glucuronide
    Biosynth
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    Scopoletin b-D-glucuronide

    CAS:
    <p>Scopoletin b-D-glucuronide is a synthetic compound that is modified by the addition of a fluorine atom to the methyl group in scopoletin. Scopoletin b-D-glucuronide has shown antiviral activity against herpes simplex virus type 1 and 2, with an IC50 value of 1.6 μM. It also has antiviral activity against HIV type 1 and HIV type 2, with an IC50 value of 0.5 μM. This compound also inhibits viral DNA synthesis, which may be due to its inhibition of host cell protein synthesis and subsequent inhibition of viral protein synthesis. Scopoletin b-D-glucuronide has been shown to have anti-inflammatory effects in a mouse model for rheumatoid arthritis, and it may be due to its suppression of prostaglandin synthesis or interference with leukocyte chemotaxis.</p>
    Formula:C16H16O10
    Purity:Min. 95%
    Molecular weight:368.29 g/mol

    Ref: 3D-MS16852

    10mg
    1,952.00€